10040 | SR/Jr | Salt Resistant | Originated from a Sprague-Dawley outbred colony developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for resistance to salt-induced hypertension (Dahl et al 1962a,b). | Rat Resource and Research Center | inbred | 12 | origin , name |
10041 | SS/Jr | Salt Sensitive | Strain originated from a colony of Sprague-Dawley outbred rats developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for sensitivity to salt-induced hypertension (Dahl et al 1962a,b, Rapp 1982) | Rat Resource and Research Center | inbred | 53 | origin , name |
1582184 | SR/JrHsd | Dahl Salt-Resistant | Substrain of Dahl SR, from a Sprague-Dawley outbred colony, selected for resistance to salt-induced hypertension (Dahl, 1962), from Dr. John P. Rapp, Medical College of Ohio, Toledo,Ohio; to Harlan in 1986. | Envigo | inbred | 9 | origin , name |
8552293 | SR/JrSeac | Dahl Salt-Resistant | Substrain of Dahl SR, from a Sprague-Dawley outbred colony, selected for resistance to salt-induced hypertension developed at Kyudo Co.,Ltd (http://www.kyudo.co.jp/) to Seac Yoshitomi, LTD Japan, now maintained at NBRP | National BioResource Project for the Rat in Japan | inbred | 1 | origin , name |
1582190 | SS/JrHsd | Dahl Salt-Sensitive | Substrain of Dahl SS, from a Sprague-Dawley outbred colony, selected for sensitivity to salt-induced hypertension (Dahl, 1962), from Dr. John P. Rapp, Medical College of Ohio, Toledo,Ohio; to Harlan in 1986. | Envigo | inbred | 13 | origin , name |
2325202 | SS/JrSeac | Dahl Salt-Sensitive | Substrain of Dahl SS, from a Sprague-Dawley outbred colony, selected for sensitivity to salt-induced hypertension developed at Kyudo Co.,Ltd (http://www.kyudo.co.jp/) to Seac Yoshitomi, LTD Japan, now maintained at NBRP | National BioResource Project for the Rat in Japan | inbred | 1 | origin , name |
724573 | SS/JrTol | Dahl salt-sensitive (SS/Jr) rats | In the 1960s, Dahl selectively bred rats for sensitivity (SS rats) to the hypertensive effect of high-salt diet. | | inbred | 14 | origin , name |
728143 | SS.LEW-(D1Mco38-D1Rat49)/Jr | | Inbred Salt-sensitive SS/Jr rats were mated to LEW/NCrl rats to create congenic strain. | | congenic | 2 | origin |
728152 | SS.LEW-(D1Rat196-D1Mgh7)/Jr | | Inbred Salt-sensitive SS/Jr rats were mated to LEW/NCrl rats to create congenic strain. | | congenic | 1 | origin |
728153 | SS.LEW-(D1Rat196-D1Rat49)/Jr | | Inbred Salt-sensitive SS/Jr rats were mated to LEW/NCrl rats to create congenic strain. | | congenic | 2 | origin |
728134 | SS.LEW-(D1Rat35-D1Rat49)/Jr | | Inbred Salt-sensitive SS/Jr rats were mated to LEW/NCrl rats to create congenic strain. | | congenic | 4 | origin |
728163 | SS.LEW-(D1Uia2-D1Rat49)/Jr | | Inbred Salt-sensitive SS/Jr rats were mated to LEW/NCrl rats to create congenic strain. | | congenic | 2 | origin |
728159 | SS.LEW-(D1Mco36-D1Rat49)/Jr | | Inbred Salt-sensitive SS/Jr rats were mated to LEW/NCrlBR rats to create congenic strain. | | congenic | 4 | origin |
728162 | SS.LEW-(D1Mco87-D1Rat71)/Jr | | Inbred Salt-sensitive SS/Jr rats were mated to LEW/NCrlBR rats to create congenic strain. | | congenic | 5 | origin |
728138 | SS.MNS-(Mme-Gca)/Ayd | | Segments from Milan normotensive rat were inserted in thre homologous region of Dahl salt-sensitive | | congenic | 2 | origin |
60985 | BN | BN | Billingham and Silvers 1958, from a brown mutation maintained by DH King and P Aptekman in a pen-bred colony (Billingham and Silvers 1959). A plasma kininogen-deficient mutant strain (BN/Ka) has been described in which release of heat-induced substance P is defective (Tang et al, 1994) and respons e to the hypertensive effects of deoxycorticosterone acetate salt is much faster than in normal BN rats (Majima et al, 1995a,b). | Charles River Laboratories | inbred | 28 | origin |
629481 | SHR.WKY-(D1Wox33-D1Got194) | | This congenic strain contains a WKY chromosome 1 segment containing QTLs affecting blood pressure and salt sensitivity transferred to the SHR background. | | congenic | 1 | origin |
329848962 | SHRSP.SHR-(D1Got82-D1Rat97)/Izm | | A subcongenic strain generated by backcrossing SHRSP.SHR-(D1Mgh5-D1Got87)/Izm (NBRP Rat No.0709, RGD:7411707) to SHRSP/Izm. A segment of the QTL region of chromosome 1 involved in salt-induced stroke (Niiya et al. Sci Rep. 2018; 8; 9403) has been exchanged. | National BioResource Project for the Rat in Japan | congenic | 1 | origin |
70453 | SR | | Rapp from a Sprague-Dawley outbred colony developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for resistance to salt-induced hypertension (Dahl et al 1962a,b). Also designated R/JR by Rapp (1984), and Dahl R by Mollegard, Copenhag en. | | inbred | 1 | origin |
737936 | SR/JrIpcv | | Substrain of SR, from a Sprague-Dawley outbred colony, selected for resistance to salt-induced hypertension (Dahl, 1962) | | inbred | 1 | origin |
737961 | SR/JrMol | | Substrain of SR, from a Sprague-Dawley outbred colony, selected for resistance to salt-induced hypertension (Dahl, 1962), from Medical College of Ohio to Mollegaard | | inbred | 1 | origin |
69369 | SS | | From a colony of Sprague-Dawley outbred rats developed by LK Dahl, Brookhaven National Laboratories, Upton, New York, selected for sensitivity to salt-induced hypertension (Dahl et al 1962a,b, Rapp 1982). Also designated S/JR by Rapp (1984), who gives an extensi ve review of the characteristics of the strain, and Dahl S by Mollegard, Copenhagen. Note that the Dahl selected strain has been independently inbred at the NIH, and designated DSS/N. There is likely to be confusion among these colonies unless considerable care is taken with nomenclature. Stlezin et al (1992) found that SS and SR had about 80% of DNA fingerprint bands in common, compared with 50% between SHR and WKY. According to Ginn et al, (1993) analysis of RFLPs and microsatellites suggest that SR is a reasonably good control strain for SS, though crosses between SS and unrelated normotensive strains will be useful in identifying the loci responsible for salt-induced hypertension. | | inbred | 3 | origin |
151893484 | SS-Tg(CAG-Fh)A1Mcwi | | This is a transgenic model created using Sleeping Beauty system. The transgenic animals are overexpressing fumarate hydratase (Fh) under the control of the ubiquitous CAG promoter in the Dahl salt-sensitive strain background. | contact MCW Rat Distribution at mcwcustomrats@mcw.edu | transgenic | 1 | origin |
728165 | SS.LEW-(D1Rat196-D1Mco36)/Jr | | Segment of chr 1 from Lewis which is an in-house colony was introgressed into Dahl salt-sensitive strain which was obtained from Charles River. | | congenic | 3 | origin |
731190 | SS.LEW-(D1Rat211-D1Rat18)/Mco | | A segment of chr 1 from Lewis which was obtained from Charles was introgressed into Dahl salt-sensitive strain which is an in-house colony. | | congenic | 2 | origin |
631610 | SS.LEW-(D1Rat39-D1Rat131)/Jr | | Segment of chr 1 from Lewis which is an in-house colony was introgressed into Dahl salt-sensitive strain which was obtained from Charles River. | | congenic | 2 | origin |
631571 | SS.LEW-(D1Uia8-D1Mco38)/Jr | | Segment of chr 1 from Lewis which was obtained from Charles was introgressed into Dahl salt-sensitive strain which is an in-house colony. | | congenic | 3 | origin |
1357987 | SS.LEW-(D1Uia8-D1Rat18)/Mco | | A 17 cM segment of chr 1 from Lewis which was obtained from Charles was introgressed into Dahl salt-sensitive strain which is an in-house colony. | | congenic | 1 | origin |
629578 | SS.LEW-(D5Rat130-D5Mco10)/Jr | | A large segment of chr. 5 from LEW was inserted into Dahl salt-sensitive (SS/Jr) background, congenic substrains were developed by crossing SS.LEW to SS for 8 generations | | congenic | 2 | origin |
1579902 | SS.LEW-(D5Rat130-D5Rat108)/JrMcwi | SS.LEW-(D5Rat130-D5Rat108)/JrMcwi | This congenic strain contains a LEW chromosome 5 segment transferred to the Dahl salt sensitive background. The strain was originally developed by Drs. Rapp and M. R. Garrett at the Medical University of Ohio and has also been maintained by brother-sister matin g at the Medical College of Wisconsin for more than 20 generations. | | congenic | 2 | origin |
1579899 | SS.LEW-(D5Rat130-D5Rat31)/JrMcwi | SS.LEW-(D5Rat130-D5Rat31)/JrMcwi | This congenic strain contains a LEW chromosome 5 segment transferred to the Dahl salt sensitive background. The strain was originally developed by Drs. Rapp and M. R. Garrett at the Medical University of Ohio and has also been maintained by brother-sister mating at the Medical College of Wisconsin for more than 20 generations. | | congenic | 2 | origin |
1579911 | SS.LEW-(D5Rat130-D5Rat72)/Mcwi | SS.LEW-(D5Rat130-D5Rat72)/Mcwi | This congenic strain contains a LEW chromosome 5 segment transferred to the Dahl salt sensitive background. | | congenic | 1 | origin |
7421649 | SS.MNS-(D2Chm153-D2Chm410)/Ayd | | Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous ra t was then backcrossed to SS/Jr rat to duplicate the fragment. | | congenic | 3 | origin |
7421647 | SS.MNS-(D2Chm161-D2Chm410)/Ayd | | Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous ra t was then backcrossed to SS/Jr rat to duplicate the fragment. | | congenic | 3 | origin |
8657399 | SS.MNS-(D2Chm214-D2Chm302)/Ayd | | Congenic substrain created by backcrossing congenic strain MNS/N strain with Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous rat was then backcrossed to SS/Jr rat to dupl icate the fragment. | | congenic | 1 | origin |
1358177 | SS.MNS-(D2Chm25-D2Mit14)/Ayd | | Congenic strain was created by backcrossing congenic strain SS.MNS-(D2Mit6-Adh1)/Lt strain into the parental Dahl Salt-sensitive (SS) strain. | | congenic | 3 | origin |
1358169 | SS.MNS-(D2Chm25-D2Rat131)/Ayd | | Congenic strain was created by backcrossing congenic strain SS.MNS-(D2Chm90-D2Wox37)/Lt strain into the parental Dahl Salt-sensitive (SS) strain. | | congenic | 7 | origin |
1358172 | SS.MNS-(D2Chm25-Fgg)/Ayd | | Congenic strain was created by backcrossing congenic strain SS.MNS-(D2Mit6-Adh1)/Lt strain into the parental Dahl Salt-sensitive (SS) strain. | | congenic | 7 | origin |
7421643 | SS.MNS-(D2Chm254-D2Chm161)/Ayd | | Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous ra t was then backcrossed to SS/Jr rat to duplicate the fragment. | | congenic | 5 | origin |
7421654 | SS.MNS-(D2Chm366-D2Rat52)/Ayd | | Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous ra t was then backcrossed to SS/Jr rat to duplicate the fragment. | | congenic | 4 | origin |
7421651 | SS.MNS-(D2Chm442-D2Chm410)/Ayd | | Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous ra t was then backcrossed to SS/Jr rat to duplicate the fragment. | | congenic | 1 | origin |
1358165 | SS.MNS-(D2Chm51-D2Rat341)/Ayd | | Congenic strain was created by backcrossing congenic strain SS.MNS-(D2Mit6-D2Rat166)/Ayd strain into the parental Dahl Salt-sensitive (SS) strain. | | congenic | 6 | origin |
728172 | SS.MNS-(D2Mit6-Adh1)/Ayd | | Segments from Milan normotensive rat were inserted in thre homologous region of Dahl salt-sensitive, the Atp1a1 gene was from MNS | | congenic | 1 | origin |
1357984 | SS.MNS-(D2Mit6-D2Rat166)/Ayd | | Congenic strain was created by backcrossing congenic strain SS.MNS-(D2Mit6-Adh1)/Lt strain into the parental Dahl Salt-sensitive (SS) strain | | congenic | 1 | origin |
1357978 | SS.MNS-(D2Mit6-D2Rat303)/Ayd | | Congenic strain was created by backcrossing congenic strain SS.MNS-(D2Mit6-Adh1)/Lt strain into the parental Dahl Salt-sensitive (SS) strain | | congenic | 2 | origin |
7421640 | SS.MNS-(D2Rat155-D2Chm161)/Ayd | | Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous ra t was then backcrossed to SS/Jr rat to duplicate the fragment. | | congenic | 3 | origin |
7421645 | SS.MNS-(D2Rat155-D2Chm419)/Ayd | | Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous ra t was then backcrossed to SS/Jr rat to duplicate the fragment. | | congenic | 4 | origin |
1358156 | SS.MNS-(D2Rat183-D2Chm113)/Ayd | | Congenic strain was created by backcrossing congenic strain SS.MNS-(D2Mit6-D2Rat166)/Lt strain into the parental Dahl Salt-sensitive (SS) strain. | | congenic | 10 | origin |
1358167 | SS.MNS-(D2Wox27-Adh1)/Ayd | | Congenic strain was created by backcrossing congenic strain SS.MNS-(D2Mit6-Adh1)/Lt strain into the parental Dahl Salt-sensitive (SS) strain. | | congenic | 2 | origin |
728170 | SS.MNS-(Mme-D2Mit14)/Ayd | | Segments from Milan normotensive rat were inserted in thre homologous region of Dahl salt-sensitive, the Atp1a1 gene was from the S strain | | congenic | 2 | origin |
1357979 | SS.MNS-(Mme-D2Rat131)/Ayd | | Congenic strain was created by backcrossing congenic strain SS.MNS-(D2Mit6-Adh1)/Lt strain into the parental Dahl Salt-sensitive (SS) strain | | congenic | 1 | origin |
10046035 | SS.SR-(D13Arb5-D13Arb8)/Mcwi | | A region of chromosome 13 containing the renin gene from the Dahl salt-resistant (Dahl R; SR/JrHsd) strain into the SS genetic background (SS/JrHsdMcwi) | | congenic | 1 | origin |
1579900 | SS.SR-(D9Rat89-Resp18)/Mco | | Congenic strain was created by backcrossing SR strain into the parental Dahl Salt-sensitive (SS) strain | | congenic | 1 | origin |