Csrp2 (cysteine and glycine-rich protein 2) - Rat Genome Database

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Gene: Csrp2 (cysteine and glycine-rich protein 2) Rattus norvegicus
Analyze
Symbol: Csrp2
Name: cysteine and glycine-rich protein 2
RGD ID: 61950
Description: Predicted to enable actinin binding activity. Predicted to be a structural constituent of muscle. Involved in myoblast differentiation. Predicted to be active in Z disc and nucleus. Orthologous to human CSRP2 (cysteine and glycine rich protein 2); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CRP2; cysteine rich protein 2; cysteine-rich protein 2; LIM/double zinc-finger protein; SmLIM; smooth muscle cell LIM protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,235,415 - 48,254,049 (+)NCBIGRCr8
mRatBN7.2746,349,109 - 46,367,743 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,348,686 - 46,367,745 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx748,248,835 - 48,267,393 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0750,451,964 - 50,470,522 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,229,694 - 50,248,252 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0753,630,675 - 53,649,309 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,630,621 - 53,649,310 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0753,641,861 - 53,660,495 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4749,910,235 - 49,929,536 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1749,930,505 - 49,949,807 (+)NCBI
Celera743,154,739 - 43,173,322 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
carbonyl sulfide  (EXP)
CGP 52608  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (EXP)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
fenthion  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
gamma-tocopherol  (ISO)
gemcitabine  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
lipopolysaccharide  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methidathion  (ISO)
milrinone  (EXP)
monocrotaline  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
ochratoxin A  (EXP)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenylephrine  (EXP)
pirinixic acid  (EXP,ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (EXP,ISO)
titanium dioxide  (ISO)
tocopherol  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)
nucleus  (IBA,IEA)
Z disc  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. LIM-only protein, CRP2, switched on smooth muscle gene activity in adult cardiac myocytes. Chang DF, etal., Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):157-62. Epub 2006 Dec 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Molecular cloning and characterization of SmLIM, a developmentally regulated LIM protein preferentially expressed in aortic smooth muscle cells. Jain MK, etal., J Biol Chem 1996 Apr 26;271(17):10194-9.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Cloning of CRP2, a novel member of the cysteine-rich protein family with two repeats of an unusual LIM/double zinc-finger motif. Okano I, etal., FEBS Lett 1993 Oct 25;333(1-2):51-5.
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
11. LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1. Weiskirchen R, etal., Biochem J 2001 Nov 1;359(Pt 3):485-96.
Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:15219810   PMID:18387947   PMID:19364329   PMID:21423176  


Genomics

Comparative Map Data
Csrp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8748,235,415 - 48,254,049 (+)NCBIGRCr8
mRatBN7.2746,349,109 - 46,367,743 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl746,348,686 - 46,367,745 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx748,248,835 - 48,267,393 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0750,451,964 - 50,470,522 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0750,229,694 - 50,248,252 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0753,630,675 - 53,649,309 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl753,630,621 - 53,649,310 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0753,641,861 - 53,660,495 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4749,910,235 - 49,929,536 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1749,930,505 - 49,949,807 (+)NCBI
Celera743,154,739 - 43,173,322 (+)NCBICelera
Cytogenetic Map7q22NCBI
CSRP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381276,858,709 - 76,879,019 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1276,858,709 - 76,879,023 (-)EnsemblGRCh38hg38GRCh38
GRCh371277,252,489 - 77,272,799 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361275,776,627 - 75,796,930 (-)NCBINCBI36Build 36hg18NCBI36
Build 341275,754,963 - 75,775,267NCBI
Celera1276,918,012 - 76,938,313 (-)NCBICelera
Cytogenetic Map12q21.2NCBI
HuRef1274,305,412 - 74,325,698 (-)NCBIHuRef
CHM1_11277,218,021 - 77,238,339 (-)NCBICHM1_1
T2T-CHM13v2.01276,836,580 - 76,856,889 (-)NCBIT2T-CHM13v2.0
Csrp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910110,756,037 - 110,775,375 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10110,755,650 - 110,775,483 (+)EnsemblGRCm39 Ensembl
GRCm3810110,920,176 - 110,939,514 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10110,919,789 - 110,939,622 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710110,357,232 - 110,376,570 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610110,324,289 - 110,343,732 (+)NCBIMGSCv36mm8
Celera10112,849,513 - 112,868,818 (+)NCBICelera
Cytogenetic Map10D1NCBI
cM Map1057.84NCBI
Csrp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540516,001,568 - 16,020,787 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540516,001,568 - 16,020,642 (-)NCBIChiLan1.0ChiLan1.0
CSRP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21084,896,312 - 84,917,192 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11284,892,703 - 84,913,035 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01274,376,871 - 74,397,168 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11277,227,481 - 77,247,732 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1277,227,481 - 77,247,557 (-)Ensemblpanpan1.1panPan2
CSRP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11519,744,074 - 19,747,109 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1520,216,652 - 20,230,291 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01520,071,536 - 20,085,201 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11519,671,196 - 19,684,832 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01519,729,070 - 19,742,682 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01519,857,892 - 19,871,540 (-)NCBIUU_Cfam_GSD_1.0
Csrp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494540,652,573 - 40,672,320 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365685,055,885 - 5,075,998 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365685,056,006 - 5,075,277 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CSRP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5104,273,168 - 104,295,141 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.15104,271,717 - 104,295,142 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.25109,449,680 - 109,475,944 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CSRP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11172,435,817 - 72,455,954 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1172,434,598 - 72,455,929 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037173,087,804 - 173,108,000 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Csrp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475021,201,462 - 21,220,268 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475021,202,106 - 21,220,268 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Csrp2
80 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:27
Count of miRNA genes:27
Interacting mature miRNAs:27
Transcripts:ENSRNOT00000067011
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72673740163902784Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)72940968353612950Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)72940968374409683Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72940968384928080Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73111283276112832Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73429328279293282Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73429328279293282Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73796056982960569Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74110969256793354Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
634326Hc3Hypercalciuria QTL 32.1urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)74278731487787314Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74322875088228750Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)743747012108555253Rat
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)743747099102228765Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)74486753389867533Rat

Markers in Region
AW551867  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22029,411,623 - 29,411,746 (+)MAPPERmRatBN7.2
Rnor_6.02031,084,910 - 31,085,032NCBIRnor6.0
Rnor_5.02032,870,358 - 32,870,480UniSTSRnor5.0
RGSC_v3.42029,590,723 - 29,590,845UniSTSRGSC3.4
Celera2030,840,412 - 30,840,534UniSTS
Cytogenetic Map20q11UniSTS
Cytogenetic Map7q13UniSTS
RH129663  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,367,517 - 46,367,707 (+)MAPPERmRatBN7.2
Rnor_6.0753,649,084 - 53,649,273NCBIRnor6.0
Rnor_5.0753,660,270 - 53,660,459UniSTSRnor5.0
RGSC_v3.4749,929,311 - 49,929,500UniSTSRGSC3.4
Celera743,173,097 - 43,173,286UniSTS
RH 3.4 Map7397.4UniSTS
Cytogenetic Map7q13UniSTS
RH135193  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,349,750 - 46,349,946 (+)MAPPERmRatBN7.2
Rnor_6.0753,631,317 - 53,631,512NCBIRnor6.0
Rnor_5.0753,642,503 - 53,642,698UniSTSRnor5.0
RGSC_v3.4749,910,877 - 49,911,072UniSTSRGSC3.4
Celera743,155,330 - 43,155,525UniSTS
RH 3.4 Map7389.6UniSTS
Cytogenetic Map7q13UniSTS
RH138817  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,358,014 - 46,358,154 (+)MAPPERmRatBN7.2
Rnor_6.0753,639,581 - 53,639,720NCBIRnor6.0
Rnor_5.0753,650,767 - 53,650,906UniSTSRnor5.0
RGSC_v3.4749,919,141 - 49,919,280UniSTSRGSC3.4
Celera743,163,594 - 43,163,733UniSTS
RH 3.4 Map7397.6UniSTS
Cytogenetic Map7q13UniSTS
RH141733  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,367,897 - 46,368,115 (+)MAPPERmRatBN7.2
Rnor_6.0753,649,464 - 53,649,681NCBIRnor6.0
Rnor_5.0753,660,650 - 53,660,867UniSTSRnor5.0
RGSC_v3.4749,929,691 - 49,929,908UniSTSRGSC3.4
Celera743,173,477 - 43,173,694UniSTS
RH 3.4 Map7396.3UniSTS
Cytogenetic Map7q13UniSTS
D3S4161  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2746,366,069 - 46,366,850 (+)MAPPERmRatBN7.2
Rnor_6.0753,647,636 - 53,648,416NCBIRnor6.0
Rnor_5.0753,658,822 - 53,659,602UniSTSRnor5.0
RGSC_v3.4749,927,863 - 49,928,643UniSTSRGSC3.4
Celera743,171,649 - 43,172,429UniSTS
Cytogenetic Map7q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 32 48 32 9 32 1 1 74 35 41 11 1
Low 11 9 9 10 9 7 10 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000067011   ⟹   ENSRNOP00000061356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,348,686 - 46,366,894 (+)Ensembl
Rnor_6.0 Ensembl753,630,621 - 53,649,295 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080598   ⟹   ENSRNOP00000075692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,349,095 - 46,367,744 (+)Ensembl
Rnor_6.0 Ensembl753,630,661 - 53,649,310 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097951   ⟹   ENSRNOP00000082765
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl746,354,868 - 46,367,745 (+)Ensembl
RefSeq Acc Id: NM_177425   ⟹   NP_803174
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8748,235,415 - 48,254,049 (+)NCBI
mRatBN7.2746,349,109 - 46,367,743 (+)NCBI
Rnor_6.0753,630,675 - 53,649,309 (+)NCBI
Rnor_5.0753,641,861 - 53,660,495 (+)NCBI
RGSC_v3.4749,910,235 - 49,929,536 (+)RGD
Celera743,154,739 - 43,173,322 (+)RGD
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_803174   ⟸   NM_177425
- UniProtKB: Q62908 (UniProtKB/Swiss-Prot),   A6IGF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000061356   ⟸   ENSRNOT00000067011
RefSeq Acc Id: ENSRNOP00000075692   ⟸   ENSRNOT00000080598
RefSeq Acc Id: ENSRNOP00000082765   ⟸   ENSRNOT00000097951
Protein Domains
LIM zinc-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62908-F1-model_v2 AlphaFold Q62908 1-193 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695186
Promoter ID:EPDNEW_R5711
Type:single initiation site
Name:Csrp2_1
Description:cysteine and glycine-rich protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0753,630,646 - 53,630,706EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61950 AgrOrtholog
BioCyc Gene G2FUF-34141 BioCyc
Ensembl Genes ENSRNOG00000003772 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067011.3 UniProtKB/TrEMBL
  ENSRNOT00000080598.2 UniProtKB/TrEMBL
  ENSRNOT00000097951 ENTREZGENE
  ENSRNOT00000097951.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7303714 IMAGE-MGC_LOAD
InterPro Znf_LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29317 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:105286 IMAGE-MGC_LOAD
NCBI Gene 29317 ENTREZGENE
PANTHER CYSTEINE AND GLYCINE-RICH PROTEIN 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO-GTPASE-ACTIVATING PROTEIN LRG1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Csrp2 PhenoGen
PROSITE LIM_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003772 RatGTEx
SMART LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2KB84_RAT UniProtKB/TrEMBL
  A0A8I5ZXR0_RAT UniProtKB/TrEMBL
  A6IGF2 ENTREZGENE, UniProtKB/TrEMBL
  A6IGF3_RAT UniProtKB/TrEMBL
  A6IGF4_RAT UniProtKB/TrEMBL
  CSRP2_RAT UniProtKB/Swiss-Prot
  G3V9V9_RAT UniProtKB/TrEMBL
  Q62908 ENTREZGENE
UniProt Secondary Q5U202 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Csrp2  cysteine and glycine-rich protein 2      Symbol and Name status set to approved 1299863 APPROVED
2005-09-30 Csrp2        Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-25   cysteine and glycine-rich protein 2  Csrp2  cysteine rich protein 2  Name updated to reflect Human and Mouse nomenclature 625702 APPROVED
2002-06-10 Csrp2  cysteine rich protein 2      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference