| 621595 | Vcp | valosin-containing protein | ENCODES a protein that exhibits ADP binding; ATP binding; ATP hydrolysis activity; INVOLVED IN endoplasmic reticulum to Golgi vesicle-mediated transport; ERAD pathway; positive regulation of ubiquitin-dependent protein catabolic process; PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; Endoplasmic Reticulum-associated degradation pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); FOUND IN cytosol; glutamatergic synapse; VCP-NPL4-UFD1 AAA ATPase complex; INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 62005984 | 62025387 | Rat | 465 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 10054274 | Vcpem1Ionsz | valosin-containing protein; CRISPR/Cas9 system induced mutant 1, Institute of Neuroscience, Chinese Academy of Sciences | mutation induced by CRISPR/Cas9 system in the Vcp gene that made the 155th amino acid Arg into His | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 1311270 | Nvl | nuclear VCP-like | ENCODES a protein that exhibits ATP binding (ortholog); preribosome binding (ortholog); INVOLVED IN positive regulation of telomere maintenance (ortholog); regulation of protein localization to nucleolus (ortholog); ribosomal large subunit biogenesis (ortholog); PARTICIPATES IN ribosome biogenesis p athway; FOUND IN nuclear exosome (RNase complex) (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 13 | 95385389 | 95438490 | Rat | 69 | name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1565432 | Svip | small VCP interacting protein | ENCODES a protein that exhibits ATPase binding (ortholog); INVOLVED IN negative regulation of ERAD pathway; negative regulation of ubiquitin-dependent protein catabolic process; negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly; FOUND IN endoplasm ic reticulum membrane (ortholog); membrane (ortholog); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 1 | 110723051 | 110728741 | Rat | 79 | old_gene_name , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563409 | Vcf1 | VCP nuclear cofactor family member 1 | INTERACTS WITH bisphenol A; cadmium dichloride; endosulfan | 10 | 99206549 | 99227471 | Rat | 40 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 2323310 | Vcf2 | VCP nuclear cofactor family member 2 | INTERACTS WITH gentamycin; paracetamol; tetrachloromethane | X | 22762022 | 22820680 | Rat | 24 | name | gene, protein-coding, INFERRED [RefSeq] |
| 628897 | Selenos | selenoprotein S | ENCODES a protein that exhibits antioxidant activity (ortholog); ATPase binding (ortholog); enzyme binding (ortholog); INVOLVED IN cell redox homeostasis (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to oxidative stress (ortholog); ASSOCIATED WITH colorectal adeno ma (ortholog); colorectal carcinoma (ortholog); Inflammation (ortholog); FOUND IN cytoplasmic microtubule (ortholog); Derlin-1 retrotranslocation complex (ortholog); Derlin-1-VIMP complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; ammonium chloride | 1 | 129070240 | 129080007 | Rat | 169 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 708520 | Vcpip1 | valosin containing protein interacting protein 1 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity; INVOLVED IN endoplasmic reticulum membrane fusion; Golgi organization; Golgi reassembly; ASSOCIATED WITH progeria (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynyles tradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 5 | 14317083 | 14343724 | Rat | 126 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1563609 | Cpvl | carboxypeptidase, vitellogenic-like | ENCODES a protein that exhibits carboxypeptidase activity (inferred); hydrolase activity (inferred); peptidase activity (inferred); INVOLVED IN proteolysis (inferred); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 84311853 | 84422098 | Rat | 78 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 7565188 | Vcpkmt | valosin containing protein lysine methyltransferase | ENCODES a protein that exhibits ATPase binding (ortholog); protein methyltransferase activity (ortholog); protein-lysine N-methyltransferase activity (ortholog); INVOLVED IN negative regulation of ATP-dependent activity (ortholog); peptidyl-lysine methylation (ortholog); peptidyl-lysine trimethylati on (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); protein-containing complex (ortholog); INTERACTS WITH 17beta-estradiol; bisphenol A; flutamide | 6 | 93772558 | 93778400 | Rat | 65 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1306577 | Faf2 | Fas associated factor family member 2 | ENCODES a protein that exhibits lipase binding (ortholog); lipase inhibitor activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN ERAD pathway (ortholog); lipid droplet organization (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog) ; ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum (ortholog); lipid droplet (ortholog); VCP-NPL4-UFD1 AAA ATPase complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 3-chloropropane-1,2-diol | 17 | 9952329 | 9994596 | Rat | 97 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 620794 | Nploc4 | NPL4 homolog, ubiquitin recognition factor | ENCODES a protein that exhibits ATPase binding; K48-linked polyubiquitin modification-dependent protein binding; K63-linked polyubiquitin modification-dependent protein binding; INVOLVED IN ERAD pathway; Golgi organization; retrograde protein transport, ER to cytosol; PARTICIPATES IN Endoplasmic Ret iculum-associated degradation pathway; FOUND IN UFD1-NPL4 complex; VCP-NPL4-UFD1 AAA ATPase complex; nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 10 | 106152756 | 106208306 | Rat | 144 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 619952 | Nsfl1c | NSFL1 cofactor | ENCODES a protein that exhibits ATPase binding; phospholipid binding; ubiquitin binding; INVOLVED IN Golgi organization; membrane fusion; establishment of mitotic spindle orientation (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN cytosol; spindle pole cent rosome; VCP-NSFL1C complex; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,5-hexanedione | 3 | 160438708 | 160463261 | Rat | 143 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306757 | Rnf125 | ring finger protein 125 | ENCODES a protein that exhibits p53 binding (ortholog); ubiquitin conjugating enzyme binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); negative regulation of RIG-I signaling pathway (ortholog); negative regulatio n of type I interferon production (ortholog); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; ASSOCIATED WITH genetic disease (ortholog); Tenorio Syndrome (ortholog); FOUND IN Golgi apparatus (ortholog); Golgi membrane (ortholog); VCP-NPL4-UFD1 AAA ATPase complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 18 | 12528995 | 12550646 | Rat | 160 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306346 | Ubxn7 | UBX domain protein 7 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); ubiquitin binding (ortholog); ubiquitin protein ligase binding (ortholog); FOUND IN nucleoplasm (ortholog); VCP-NPL4-UFD1 AAA ATPase complex (ortholog ); INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; bisphenol A | 11 | 81932944 | 81965142 | Rat | 79 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1306346 | Ubxn7 | UBX domain protein 7 | ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); ubiquitin binding (ortholog); ubiquitin protein ligase binding (ortholog); FOUND IN nucleoplasm (ortholog); VCP-NPL4-UFD1 AAA ATPase complex (ortholog ); INTERACTS WITH 17alpha-ethynylestradiol; 3-chloropropane-1,2-diol; bisphenol A | 11 | 81903235 | 81920998 | Rat | 79 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 619822 | Ufd1 | ubiquitin recognition factor in ER associated degradation 1 | ENCODES a protein that exhibits ATPase binding; protein-containing complex binding; signaling receptor binding; INVOLVED IN ERAD pathway; retrograde protein transport, ER to cytosol; cellular response to misfolded protein (ortholog); PARTICIPATES IN schizophrenia pathway; Endoplasmic Reticulum-assoc iated degradation pathway; ASSOCIATED WITH congenital heart disease (ortholog); Craniofacial Abnormalities (ortholog); DiGeorge syndrome (ortholog); FOUND IN UFD1-NPL4 complex; VCP-NPL4-UFD1 AAA ATPase complex; cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene | 11 | 95665971 | 95689423 | Rat | 161 | description | gene, protein-coding, VALIDATED [RefSeq] |