| 1583689 | Ugt1a5 | UDP glucuronosyltransferase family 1 member A5 | ENCODES a protein that exhibits enzyme binding (ortholog); glucuronosyltransferase activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN cellular response to ethanol; cellular response to glucocorticoid stimulus; cellular response to hormone stimulus; PARTICIPATES IN nicot ine pharmacodynamics pathway; nicotine pharmacokinetics pathway; phenytoin pharmacodynamics pathway; ASSOCIATED WITH celiac disease (ortholog); Crigler-Najjar syndrome (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH (-)-cotinine (ortholog); (5Z,8Z,11Z,13E)-15-HETE (ortholog); (S)-nicotine (ortholog) | 9 | 96210053 | 96256264 | Rat | 175 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 3935 | Ugt1a1 | UDP glucuronosyltransferase family 1 member A1 | ENCODES a protein that exhibits enzyme binding; glucuronosyltransferase activity; enzyme inhibitor activity (ortholog); INVOLVED IN acute-phase response; animal organ regeneration; biphenyl catabolic process; PARTICIPATES IN axitinib pharmacokinetics pathway; codeine and morphine pharmacodynamics pa thway; codeine and morphine pharmacokinetics pathway; ASSOCIATED WITH abnormal renal water reabsorption; decreased mean corpuscular volume; decreased urine osmolality; ASSOCIATED WITH bilirubin metabolic disorder; Crigler-Najjar syndrome; hyperthyroidism; FOUND IN cytochrome complex; endoplasmic reticulum; catalytic complex (ortholog); INTERACTS WITH (R,R,R)-alpha-tocopherol; 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene; 1-naphthyl isothiocyanate | 9 | 96249143 | 96256264 | Rat | 820 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1549741 | Ugt1a2 | UDP glucuronosyltransferase 1 family, polypeptide A2 | ENCODES a protein that exhibits enzyme binding (ortholog); glucuronosyltransferase activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN animal organ regeneration; liver development; bile acid secretion (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics path way; codeine and morphine pharmacokinetics pathway; ibuprofen pharmacodynamics pathway; ASSOCIATED WITH Crigler-Najjar syndrome (ortholog); Gilbert syndrome (ortholog); schizophrenia (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene | 9 | 96239019 | 96256264 | Rat | 302 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1549728 | Ugt1a3 | UDP glycosyltransferase 1 family, polypeptide A3 | ENCODES a protein that exhibits glucuronosyltransferase activity (ortholog); INVOLVED IN animal organ regeneration; bile acid secretion (ortholog); estrogen metabolic process (ortholog); PARTICIPATES IN ascorbate and aldarate metabolic pathway; O-linked glycan biosynthetic pathway; pentose and glucu ronate interconversion pathway; ASSOCIATED WITH Crigler-Najjar syndrome (ortholog); Gilbert syndrome (ortholog); Leber congenital amaurosis (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 96228134 | 96256264 | Rat | 79 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620949 | Ugt1a6a | UDP glucuronosyltransferase family 1 member A6a | ENCODES a protein that exhibits protein-containing complex binding; enzyme binding (ortholog); glucuronosyltransferase activity (ortholog); INVOLVED IN 4-chlorobiphenyl metabolic process; cellular response to glucocorticoid stimulus; cellular response to hormone stimulus; PARTICIPATES IN paracetamol pharmacokinetics pathway; phenytoin pharmacodynamics pathway; ascorbate and aldarate metabolic pathway; ASSOCIATED WITH type 2 diabetes mellitus; autism spectrum disorder (ortholog); contact dermatitis (ortholog); FOUND IN protein-containing complex; endoplasmic reticulum (ortholog); INTERACTS WITH 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene; 1,7-phenanthroline; 1-naphthol | 9 | 96195018 | 96256264 | Rat | 437 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620950 | Ugt1a7c | UDP glucuronosyltransferase 1 family, polypeptide A7C | ENCODES a protein that exhibits glucuronosyltransferase activity; INVOLVED IN coumarin catabolic process; estrogen catabolic process; liver development; PARTICIPATES IN ascorbate and aldarate metabolic pathway; O-linked glycan biosynthetic pathway; pentose and glucuronate interconversion pathway; AS SOCIATED WITH type 2 diabetes mellitus; alcoholic pancreatitis (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); INTERACTS WITH 1-naphthol; 17alpha-ethynylestradiol; 17beta-estradiol | 9 | 96187382 | 96256264 | Rat | 95 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 708474 | Ugt1a8 | UDP glucuronosyltransferase family 1 member A8 | ENCODES a protein that exhibits glucuronosyltransferase activity; INVOLVED IN cellular response to 3-methylcholanthrene; coumarin catabolic process; steroid metabolic process (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; myc ophenolic acid pharmacokinetics pathway; ASSOCIATED WITH Crigler-Najjar syndrome (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); membrane (inferred); INTERACTS WITH 1-naphthol; 17alpha-ethynylestradiol; 4-methylumbelliferone | 9 | 96174899 | 96256264 | Rat | 66 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1549771 | Ugt1a9 | UDP glucuronosyltransferase family 1 member A9 | ENCODES a protein that exhibits enzyme binding (ortholog); enzyme inhibitor activity (ortholog); glucuronosyltransferase activity (ortholog); INVOLVED IN flavone metabolic process (ortholog); flavonoid metabolic process (ortholog); negative regulation of fatty acid metabolic process (ortholog); PART ICIPATES IN artemether pharmacokinetics pathway; ibuprofen pharmacodynamics pathway; ibuprofen pharmacokinetics pathway; ASSOCIATED WITH acute kidney failure (ortholog); Chemical and Drug Induced Liver Injury (ortholog); cholangiocarcinoma (ortholog); FOUND IN catalytic complex (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; amphotericin B | 9 | 96144786 | 96256264 | Rat | 317 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |