ENCODES a protein that exhibits ubiquitin activating enzyme activity (ortholog); INVOLVED IN DNA damage response (ortholog); PARTICIPATES IN Parkinson's disease pathway; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH genetic disease (ortholog); squamous cell carcinoma (ortholog); VEXAS sy
ndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); desmosome (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,5-hexanedione; 4,4'-sulfonyldiphenol
ENCODES a protein that exhibits ubiquitin activating enzyme activity (ortholog); INVOLVED IN spermatogenesis; PARTICIPATES IN altered ubiquitin/proteasome degradation pathway; Alzheimer's disease pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 3,7-dihydropurine-6-thione; 6-propyl-2
ENCODES a protein that exhibits ATP binding (inferred); ligase activity (inferred); nucleotide binding (inferred); INVOLVED IN protein ubiquitination (inferred)