| 1305894 | Tcf7 | transcription factor 7 | ENCODES a protein that exhibits beta-catenin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN alpha-beta T cell differentiation (ortholog); canonical Wnt signaling pathway (ortholog); cellular response to interleukin-4 (ortholog); PARTICIP ATES IN Wnt signaling, canonical pathway; acute myeloid leukemia pathway; arrhythmogenic right ventricular cardiomyopathy pathway; ASSOCIATED WITH Crohn's disease (ortholog); Mycoplasma pneumoniae pneumonia (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN euchromatin (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine | 10 | 36924363 | 36954279 | Rat | 200 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1311671 | Tcf7l1 | transcription factor 7 like 1 | ENCODES a protein that exhibits beta-catenin binding (ortholog); chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN anterior/posterior axis specification, embryo (ortholog); axial mesoderm morphogenesis (ortholog); negative regulation of DNA-templated transcription (ortholog); PARTICI PATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH Thyroid Neoplasms (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide | 4 | 106238892 | 106404012 | Rat | 141 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1583621 | Tcf7l2 | transcription factor 7 like 2 | ENCODES a protein that exhibits promoter-specific chromatin binding; armadillo repeat domain binding (ortholog); beta-catenin binding (ortholog); INVOLVED IN negative regulation of extrinsic apoptotic signaling pathway; negative regulation of gluconeogenesis; negative regulation of transcription by RNA polymerase II; PARTICIPATES IN altered Wnt signaling, canonical pathway; pancreatic cancer pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH type 2 diabetes mellitus; adenocarcinoma (ortholog); Animal Disease Models (ortholog); FOUND IN beta-catenin-TCF7L2 complex (ortholog); catenin-TCF7L2 complex (ortholog); chromatin (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1 | 1 | 264791335 | 264984225 | Rat | 362 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 5509981 | Tcf7l2em1Mcwi | transcription factor 7-like 2 (T-cell specific, HMG-box); zinc finger nuclease induced mutant 1, Medical College of Wisconsin | This allele was made by ZFN mutagenesis. The resulting mutation is a 169-bp deletion of exon5 and intron 5 (del 262106289 262106457) | | | | Rat | | symbol , old_gene_symbol | gene, allele |
| 69271 | Tcf4 | transcription factor 4 | ENCODES a protein that exhibits bHLH transcription factor binding; double-stranded DNA binding; beta-catenin binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II; endothelial cell activation (ortholog); negative regulation of angiogenesis (ortholog); ASSOCIATED W ITH autism spectrum disorder (ortholog); Corneal Dystrophy, Fuchs Endothelial, 3 (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN beta-catenin-TCF complex (ortholog); beta-catenin-TCF7L2 complex (ortholog); chromatin (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 18 | 65216840 | 65563186 | Rat | 292 | description | gene, protein-coding, VALIDATED [RefSeq] |