| 628859 | Tank | TRAF family member-associated NFKB activator | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); deubiquitinase activator activity (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to interleukin-1 (ortholog); cellular response to ionizing radiation (ortholog); cellular response to tu mor necrosis factor (ortholog); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; ASSOCIATED WITH autistic disorder (ortholog); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleolus (ortholog); INTERACTS WITH 17beta-estradiol; 3-methylcholanthrene; ammonium chloride | 3 | 66522834 | 66598864 | Rat | 135 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] | | 1588588 | Tbk1 | TANK-binding kinase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); nucleic acid binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); antiviral innate immune response (ortholog); cytoplasmic pattern recognition receptor signaling pathw ay (ortholog); PARTICIPATES IN Toll-like receptor signaling pathway; hepatitis C pathway; influenza A pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); AUTOINFLAMMATION WITH ARTHRITIS AND VASCULITIS (ortholog); ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), 8 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil | 7 | 58963319 | 58996357 | Rat | 241 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] | | 631328 | Tbkbp1 | TBK1 binding protein 1 | ENCODES a protein that exhibits metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN immune system process (inferred); innate immune response (inferred); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; ASSOCIATED WITH ankylosing spondylitis (or tholog); INTERACTS WITH (+)-schisandrin B; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 82616978 | 82632169 | Rat | 69 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] | | 1308784 | Tnks | tankyrase | ENCODES a protein that exhibits histone binding (ortholog); NAD+ poly-ADP-ribosyltransferase activity (ortholog); NAD+-protein mono-ADP-ribosyltransferase activity (ortholog); INVOLVED IN cellular response to nutrient; negative regulation of maintenance of mitotic sister chromatid cohesion, telomeri c (ortholog); negative regulation of telomere maintenance via telomere lengthening (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUND IN chromosome, telomeric region (ortholog); cytosol (ortholog); Golgi apparatus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 63922969 | 64073972 | Rat | 119 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] | | 1305026 | Tnks2 | tankyrase 2 | ENCODES a protein that exhibits enzyme binding (ortholog); NAD+ poly-ADP-ribosyltransferase activity (ortholog); NAD+-protein mono-ADP-ribosyltransferase activity (ortholog); INVOLVED IN multicellular organism growth (ortholog); negative regulation of telomere maintenance via telomere lengthening (o rtholog); positive regulation of canonical Wnt signaling pathway (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; FOUND IN cytoplasm (ortholog); nuclear envelope (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol | 1 | 243980432 | 244033629 | Rat | 126 | old_gene_name , name | gene, protein-coding, PROVISIONAL [RefSeq] | | 1312021 | Tnks1bp1 | tankyrase 1 binding protein 1 | ENCODES a protein that exhibits ankyrin repeat binding (ortholog); enzyme binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN cellular response to ionizing radiation (ortholog); double-strand break repair (ortholog); ASSOCIATED WITH myoepithelioma (ortholog ); FOUND IN adherens junction (ortholog); CCR4-NOT complex (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 3 | 90542006 | 90566720 | Rat | 131 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] | |