| 3752 | Spp1 | secreted phosphoprotein 1 | ENCODES a protein that exhibits calcium ion binding (ortholog); extracellular matrix binding (ortholog); integrin binding (ortholog); INVOLVED IN cell adhesion; cell differentiation; negative regulation of collateral sprouting of intact axon in response to injury; PARTICIPATES IN diabetic nephropath y pathway; c-Jun N-terminal kinases MAPK signaling pathway; fibroblast growth factor signaling pathway; ASSOCIATED WITH Albuminuria; autosomal dominant polycystic kidney disease; calcinosis; FOUND IN cell projection; extracellular space; perinuclear region of cytoplasm; INTERACTS WITH (R,R)-tramadol; (S)-naringenin; 1,3,5-trinitro-1,3,5-triazinane | 14 | 5613569 | 5620695 | Rat | 899 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 11553895 | Spp1em1Mcwi | secreted phosphoprotein 1; CRISPR/Cas9 induced mutant 1, Medical College of Wisconsin | This allele was made by CRISPR/Cas9 system. The resulting mutation is a 5-bp deletion in Exon 3 of the Spp1 gene. | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 13792814 | Spp1em2Mcwi | secreted phosphoprotein 1; CRISPR/Cas9 induced mutant 2, Mcwi | CRISPR/Cas9 system was used to introduce a mutation in the Spp1 gene of SHRSP/A3NCrl rat embryos. The resulting mutation is a 11-bp deletion in Exon 3 of the Spp1 gene. | | | | Rat | | symbol , description | gene, allele |
| 13207528 | spp1em3Mcwi | secreted phosphoprotein 1; CRISPR/Cas9 induced mutant3, Mcwi | CRISPR/Cas9 system was used to introduce a mutation in the Spp1 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 4-bp deletion in Exon 3 of the Spp1 gene. | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 13207530 | Spp1em4Mcwi | secreted phosphoprotein 1; CRISPR/Cas9 induced mutant4, Mcwi | CRISPR/Cas9 system was used to introduce a mutation in the Spp1 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 5-bp deletion in Exon 3 of the Spp1 gene. | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 727829 | Sgpp1 | sphingosine-1-phosphate phosphatase 1 | ENCODES a protein that exhibits sphingosine-1-phosphate phosphatase activity (ortholog); INVOLVED IN ER to Golgi ceramide transport (ortholog); extrinsic apoptotic signaling pathway (ortholog); intrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN sphingosine 1-phosphate signaling pathwa y; sphingolipid metabolic pathway; FOUND IN endoplasmic reticulum (ortholog); membrane (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 6 | 100161024 | 100182214 | Rat | 140 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |