| 3224 | Slc22a1 | solute carrier family 22 member 1 | ENCODES a protein that exhibits acetylcholine transmembrane transporter activity; dopamine:sodium symporter activity; identical protein binding; INVOLVED IN acetylcholine transport; cellular detoxification; dopamine transport; PARTICIPATES IN lamivudine pharmacokinetics pathway; metformin pharmacoki netics pathway; tramadol pharmacokinetics pathway; ASSOCIATED WITH acute kidney failure; asthma; Endotoxemia; FOUND IN apical plasma membrane; basolateral plasma membrane; plasma membrane; INTERACTS WITH (+)-schisandrin B; (R)-carnitine; 17alpha-ethynylestradiol | 1 | 50624339 | 50651437 | Rat | 559 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12904734 | Slc22a1em1Sage | solute carrier family 22 member 1; ZFN induced mutant 1, Sage | This ZFN induced allele contains 11 bp bi-allelic deletion within exon 1 of the Slc22a1. The homozygous knockout rats display total loss of protein via Western blot. | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 621628 | Slc22a12 | solute carrier family 22 member 12 | ENCODES a protein that exhibits PDZ domain binding (ortholog); urate transmembrane transporter activity (ortholog); INVOLVED IN cellular response to insulin stimulus; renal urate salt excretion; urate transport; ASSOCIATED WITH diabetes mellitus; acute kidney failure (ortholog); Congenital Abnormali ties (ortholog); FOUND IN apical plasma membrane; brush border membrane (ortholog); membrane (ortholog); INTERACTS WITH 2-hydroxypropanoic acid; 6-propyl-2-thiouracil; 7,9-dihydro-1H-purine-2,6,8(3H)-trione | 1 | 213274266 | 213282793 | Rat | 179 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306840 | Slc22a13 | solute carrier family 22 member 13 | ENCODES a protein that exhibits nicotinate transmembrane transporter activity (ortholog); urate transmembrane transporter activity (ortholog); INVOLVED IN negative regulation of fatty acid metabolic process (ortholog); nicotinate transport (ortholog); positive regulation of T cell mediated cytotoxic ity directed against tumor cell target (ortholog); PARTICIPATES IN nicotinamide adenine dinucleotide metabolic pathway; FOUND IN apical plasma membrane (ortholog); endoplasmic reticulum (ortholog); Golgi apparatus (ortholog); INTERACTS WITH bisphenol A; cyclosporin A; methamphetamine | 8 | 127800097 | 127811750 | Rat | 55 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306470 | Slc22a14 | solute carrier family 22, member 14 | ENCODES a protein that exhibits riboflavin transmembrane transporter activity (ortholog); INVOLVED IN flagellated sperm motility (ortholog); sperm capacitation (ortholog); FOUND IN mitochondrial inner membrane (ortholog); sperm principal piece (ortholog); INTERACTS WITH bisphenol A; trichloroethene; 2,3',4,4',5-Pentachlorobiphenyl (ortholog) | 8 | 127772275 | 127794222 | Rat | 34 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1311184 | Slc22a15 | solute carrier family 22, member 15 | ENCODES a protein that exhibits amino-acid betaine transmembrane transporter activity (ortholog); INVOLVED IN amino-acid betaine transport (inferred); transmembrane transport (inferred); ASSOCIATED WITH Colorectal Neoplasms (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 3,3',5,5'-te trabromobisphenol A; acrylamide; amphetamine | 2 | 191987409 | 192049859 | Rat | 94 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1592810 | Slc22a16 | solute carrier family 22 member 16 | ENCODES a protein that exhibits amine transmembrane transporter activity (ortholog); carnitine transmembrane transporter activity (ortholog); spermidine transmembrane transporter activity (ortholog); INVOLVED IN acid secretion (ortholog); carnitine transmembrane transport (ortholog); carnitine trans port (ortholog); PARTICIPATES IN doxorubicin pharmacokinetics pathway; ASSOCIATED WITH COVID-19 (ortholog); juvenile rheumatoid arthritis (ortholog); FOUND IN membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine (ortholog); 1-methylnicotinamide (ortholog); 2-palmitoylglycerol (ortholog) | 20 | 45527275 | 45647675 | Rat | 48 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 631405 | Slc22a17 | solute carrier family 22, member 17 | ENCODES a protein that exhibits transmembrane signaling receptor activity (ortholog); INVOLVED IN siderophore transport (ortholog); FOUND IN organelle membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; 17alpha-ethynylestradiol | 15 | 32352273 | 32358780 | Rat | 93 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1303323 | Slc22a18 | solute carrier family 22, member 18 | ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN xenobiotic detoxification by transmembrane export across the plasma membrane (ortholog); xenobiotic transport (ortholog); ASSOCIATED WITH breast adenocarcinoma (ortholog); breast cancer (ortholog); Breast Neopla sms (ortholog); FOUND IN apical plasma membrane (ortholog); cytoplasm (ortholog); nuclear envelope (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 1 | 208100032 | 208124382 | Rat | 154 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628885 | Slc22a19 | solute carrier family 22, member 19 | ENCODES a protein that exhibits toxin transmembrane transporter activity (ortholog); transmembrane transporter activity (ortholog); INVOLVED IN response to molecule of fungal origin; sodium-independent organic anion transport; organic anion transport (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); FOUND IN apical plasma membrane; INTERACTS WITH 17beta-estradiol; 4-methylumbelliferone sulfate; acetamide | 1 | 214339594 | 214394681 | Rat | 69 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1583222 | Slc22a13l1 | solute carrier family 22 member 13-like 1 | ENCODES a protein that exhibits transmembrane transporter activity (inferred); INVOLVED IN transmembrane transport (inferred); FOUND IN membrane (inferred); INTERACTS WITH trichloroethene | 8 | 127838075 | 127850337 | Rat | 5 | symbol , old_gene_name , PhenoGen | gene, protein-coding, MODEL [RefSeq] |