ENCODES a protein that exhibits transcription cis-regulatory region binding; ubiquitin protein ligase activity (ortholog); INVOLVED IN negative regulation of Schwann cell proliferation; positive regulation of myelination; positive regulation of transcription by RNA polymerase II; ASSOCIATED WITH Car
diotoxicity (ortholog); FOUND IN extrinsic component of postsynaptic density membrane; glutamatergic synapse; nucleus; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene
ENCODES a protein that exhibits ubiquitin-protein transferase activity (ortholog); INVOLVED IN ERAD pathway (ortholog); protein ubiquitination (ortholog); ASSOCIATED WITH depressive disorder; juvenile rheumatoid arthritis (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-