ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
ENCODES a protein that exhibits p53 binding (ortholog); protease binding (ortholog); protein kinase binding (ortholog); INVOLVED IN intracellular protein transport (ortholog); negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of s
ignal transduction by p53 class mediator (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH shortened QT interval; ASSOCIATED WITH hypertension; FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); endosome membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent activity, acting on DNA (inferred); INVOLVED IN chromosome organization (ortholog); DNA damage response (ortholog); interstrand cross-link repair (ortholog); ASSOCIATED WITH breast cancer (ortho
log); hereditary breast ovarian cancer syndrome (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN chromosome, telomeric region (ortholog); cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,2-dichloroethane (ortholog); 1,2-dimethylhydrazine (ortholog); 17beta-estradiol (ortholog)