| 3453 | Ptprf | protein tyrosine phosphatase, receptor type, F | ENCODES a protein that exhibits insulin receptor binding; phosphate ion binding; protein tyrosine phosphatase activity; INVOLVED IN homophilic cell-cell adhesion; negative regulation of cell population proliferation; negative regulation of cell projection organization; PARTICIPATES IN insulin signal ing pathway; ASSOCIATED WITH obesity; Aplasia or Hypoplasia of Breasts and/or Nipples 2 (ortholog); congestive heart failure (ortholog); FOUND IN endosome; excitatory synapse; growth cone; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 17beta-estradiol | 5 | 137027376 | 137109405 | Rat | 268 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 2313459 | Ppfia2Tn(sb-T2/Bart3)2.339Mcwi | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2; transposon insertion 2.339, Medical College of Wisconsin | this mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 5th intron of the Ppfia2 gene | | | | Rat | | name | gene, allele |
| 1309009 | Ppfia1 | PPFI scaffold protein A1 | ENCODES a protein that exhibits PDZ domain binding; INVOLVED IN positive regulation of AMPA glutamate receptor clustering; regulation of postsynaptic membrane neurotransmitter receptor levels; cortical microtubule organization (ortholog); FOUND IN axon; dendrite; growth cone; INTERACTS WITH 2,3,7,8- tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 209070608 | 209147740 | Rat | 92 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1305021 | Ppfia2 | PPFI scaffold protein A2 | ENCODES a protein that exhibits structural constituent of postsynaptic density; structural constituent of presynapse; protein-containing complex binding (ortholog); INVOLVED IN regulation of synaptic vesicle exocytosis; dense core granule cytoskeletal transport (ortholog); regulation of dendritic sp ine development (ortholog); FOUND IN glutamatergic synapse; postsynaptic density; postsynaptic specialization; INTERACTS WITH (+)-schisandrin B; bisphenol A; C60 fullerene | 7 | 43652258 | 44126555 | Rat | 75 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 620054 | Ppfia3 | PPFI scaffold protein A3 | INVOLVED IN neurotransmitter secretion; regulation of short-term neuronal synaptic plasticity; synaptic vesicle docking (ortholog); ASSOCIATED WITH genetic disease (ortholog); Hao-Fountain Syndrome (ortholog); FOUND IN acrosomal vesicle; cytoplasm; epididymosome; INTERACTS WITH 2,2',4,4'-Tetrabromod iphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 1 | 104953598 | 104982373 | Rat | 103 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620055 | Ppfia4 | PPFI scaffold protein A4 | ASSOCIATED WITH atrial fibrillation (ortholog); FOUND IN glutamatergic synapse (ortholog); parallel fiber to Purkinje cell synapse (ortholog); presynapse (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acrylamide | 13 | 48305844 | 48354329 | Rat | 121 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1310010 | Ppfibp1 | PPFIB scaffold protein 1 | INVOLVED IN cortical microtubule organization (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); Neurodevelopmental Disorder with Seizures, Microcephaly, and Brain Abnormalities (ortholog); FOUND IN cell cortex (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-e stradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 4 | 181538249 | 181682079 | Rat | 139 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1308360 | Trio | trio Rho guanine nucleotide exchange factor | ENCODES a protein that exhibits enzyme binding; INVOLVED IN modulation of chemical synaptic transmission; negative regulation of fat cell differentiation (ortholog); neuron projection morphogenesis (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); autism spectrum disorder (ortholog); au tistic disorder (ortholog); FOUND IN glutamatergic synapse; postsynapse; Schaffer collateral - CA1 synapse; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 80235485 | 80531824 | Rat | 194 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1565383 | Ppfibp2 | PPFIB scaffold protein 2 | ENCODES a protein that exhibits identical protein binding (ortholog); ASSOCIATED WITH Familial Prostate Cancer (ortholog); Prostatic Neoplasms (ortholog); FOUND IN presynapse; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 170916649 | 171062096 | Rat | 123 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |