| 620297 | Psd | pleckstrin and Sec7 domain containing | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN maintenance of postsynaptic density structure; neuron differentiation; regulation of postsynapse assembly; PARTICIPATES IN endocytosis pathway; FOUND IN glutamatergic synapse; cleavage furrow (ortholog ); dendritic spine (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 255114703 | 255130151 | Rat | 104 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 68424 | Dlg4 | discs large MAGUK scaffold protein 4 | ENCODES a protein that exhibits acetylcholine receptor binding; beta-1 adrenergic receptor binding; beta-2 adrenergic receptor binding; INVOLVED IN AMPA glutamate receptor clustering; cerebral cortex development; dendritic spine morphogenesis; PARTICIPATES IN glutamate signaling pathway; Huntington' s disease pathway; ASSOCIATED WITH Cancer Pain; Hyperalgesia; Parkinson's disease; FOUND IN cell-cell junction; dendrite; dendrite cytoplasm; INTERACTS WITH (R)-lipoic acid; (S)-nicotine; 17beta-estradiol | 10 | 55239397 | 55267780 | Rat | 599 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 628725 | Homer1 | homer scaffold protein 1 | ENCODES a protein that exhibits G protein-coupled glutamate receptor binding; molecular adaptor activity; protein-containing complex binding; INVOLVED IN cellular response to L-glutamate; circadian rhythm; G protein-coupled glutamate receptor signaling pathway; PARTICIPATES IN glutamate signaling pa thway; ASSOCIATED WITH anxiety disorder; cocaine dependence; temporal lobe epilepsy; FOUND IN dendrite; dendritic shaft; dendritic spine; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 17beta-estradiol | 2 | 26279012 | 26388279 | Rat | 270 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 708565 | Lzts1 | leucine zipper tumor suppressor 1 | INVOLVED IN regulation of dendrite morphogenesis; regulation of synaptic plasticity; negative regulation of macroautophagy (ortholog); ASSOCIATED WITH breast carcinoma (ortholog); esophageal cancer (ortholog); Esophageal Neoplasms (ortholog); FOUND IN apical plasma membrane; cell body; dendritic sha ft; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 16 | 25309502 | 25364942 | Rat | 120 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 68423 | Dlg3 | discs large MAGUK scaffold protein 3 | ENCODES a protein that exhibits ionotropic glutamate receptor binding; PDZ domain binding; protein domain specific binding; INVOLVED IN establishment of planar polarity (ortholog); establishment or maintenance of epithelial cell apical/basal polarity (ortholog); regulation of postsynaptic membrane n eurotransmitter receptor levels (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN dendritic shaft; glutamatergic synapse; growth cone; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol | X | 69899694 | 69951928 | Rat | 180 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620223 | Dlgap1 | DLG associated protein 1 | ENCODES a protein that exhibits protein domain specific binding; protein-containing complex binding; structural constituent of postsynaptic density; INVOLVED IN aggresome assembly; modulation of chemical synaptic transmission; protein localization to synapse; PARTICIPATES IN glutamate signaling path way; ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse; postsynaptic density, intracellular component; postsynaptic membrane; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 117304144 | 118173463 | Rat | 141 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 620224 | Dlgap2 | DLG associated protein 2 | ENCODES a protein that exhibits protein domain specific binding; INVOLVED IN modulation of chemical synaptic transmission (ortholog); ASSOCIATED WITH autistic disorder (ortholog); FOUND IN dendrite; dendritic spine; glutamatergic synapse (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride | 16 | 81489059 | 82198693 | Rat | 88 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 708349 | Dlgap3 | DLG associated protein 3 | ENCODES a protein that exhibits molecular adaptor activity; PDZ domain binding; protein domain specific binding; INVOLVED IN protein-containing complex assembly; modification of postsynaptic structure (ortholog); modulation of chemical synaptic transmission (ortholog); FOUND IN dendritic spine; neur onal cell body; postsynaptic density; INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; ammonium chloride | 5 | 144776414 | 144847097 | Rat | 82 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 708350 | Dlgap4 | DLG associated protein 4 | ENCODES a protein that exhibits protein domain specific binding; INVOLVED IN modification of postsynaptic structure (ortholog); regulation of synapse maturation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); FOUND IN dendrite; neuronal cell body; cholinergic synapse (ortholog); INT ERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl | 3 | 165584271 | 165731868 | Rat | 144 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 619895 | Dlg2 | discs large MAGUK scaffold protein 2 | ENCODES a protein that exhibits PDZ domain binding; protein phosphatase binding; protein-containing complex binding; INVOLVED IN neuronal ion channel clustering; receptor clustering; anterograde axonal protein transport (ortholog); ASSOCIATED WITH melanoma (ortholog); schizophrenia (ortholog); FOUND IN dendrite; glutamatergic synapse; juxtaparanode region of axon; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 153864545 | 155916238 | Rat | 172 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 70554 | Tamalin | trafficking regulator and scaffold protein tamalin | ENCODES a protein that exhibits identical protein binding; PDZ domain binding; small GTPase binding; INVOLVED IN regulation of postsynaptic neurotransmitter receptor internalization (ortholog); signal transduction (ortholog); ASSOCIATED WITH schizophrenia; syndromic microphthalmia 5 (ortholog); FOUN D IN glutamatergic synapse; postsynaptic density; plasma membrane (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 7 | 134217612 | 134225378 | Rat | 100 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311075 | Psd2 | pleckstrin and Sec7 domain containing 2 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); phospholipid binding (inferred); INVOLVED IN regulation of ARF protein signal transduction (inferred); PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH pre-malignant neoplasm (ortholog); FOUND IN cleavage furr ow (ortholog); dendrite (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 18 | 27838943 | 27890712 | Rat | 62 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1559968 | Psd3 | pleckstrin and Sec7 domain containing 3 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN regulation of ARF protein signal transduction (inferred); PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH amphetamine abuse (ortholog); Contracture (ortholog); high grade glioma (ortholog); FOUND IN cleavage furrow (ortholog); glutamatergic synapse (ortholog); membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 16 | 26238595 | 26802535 | Rat | 137 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1310289 | Psd4 | pleckstrin and Sec7 domain containing 4 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); lipid binding (inferred); phospholipid binding (inferred); INVOLVED IN regulation of ARF protein signal transduction (inferred); PARTICIPATES IN endocytosis pathway; FOUND IN cleavage furrow (ortholog); ruffle mem brane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide | 3 | 27535341 | 27571850 | Rat | 72 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |