| 3277 | Pdc | phosducin | INVOLVED IN regulation of G protein-coupled receptor signaling pathway (inferred); visual perception (inferred); FOUND IN photoreceptor outer segment (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride | 13 | 64847366 | 64921865 | Rat | 22 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 5687695 | Pdcem2Mcwi | phosducin; zinc finger nuclease induced mutant 2, Medical College of Wisconsin | This allele was made by ZFN mutagenesis. The resulting mutation is a 14-bp deletion in exon 5 (del 489-502) | | | | Rat | | symbol , old_gene_symbol | gene, allele |
| 5687712 | Pdcem3Mcwi | phosducin; zinc finger nuclease induced mutant 3, Medical College of Wisconsin | This allele was made by ZFN mutagenesis. The resulting mutation is a net 47-bp deletion in exon 5 (del 450-501, ins. Catcg) | | | | Rat | | symbol , old_gene_symbol | gene, allele |
| 619859 | Dlat | dihydrolipoamide S-acetyltransferase | ENCODES a protein that exhibits dihydrolipoyllysine-residue acetyltransferase activity; acetyltransferase activity (ortholog); identical protein binding (ortholog); INVOLVED IN pyruvate decarboxylation to acetyl-CoA; pyruvate catabolic process (ortholog); tricarboxylic acid cycle (ortholog); PARTICI PATES IN citric acid cycle pathway; fumaric aciduria pathway; Leigh disease pathway; ASSOCIATED WITH Sleep Deprivation; Chemical and Drug Induced Liver Injury (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix; pyruvate dehydrogenase complex; mitochondrion (ortholog); INTERACTS WITH (R)-adrenaline; 17alpha-ethynylestradiol; 2,2,2-tetramine | 8 | 59875537 | 59900947 | Rat | 215 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621135 | Pdcl | phosducin like | ENCODES a protein that exhibits protein-containing complex binding; INVOLVED IN negative regulation of protein refolding; protein folding; heterotrimeric G-protein complex assembly (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 3H-1,2-dithiole-3-thione; ammonium chloride; bisphenol A | 3 | 41519953 | 41529545 | Rat | 66 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311658 | Pdcd1 | programmed cell death 1 | ENCODES a protein that exhibits signaling receptor activity (ortholog); transmembrane signaling receptor activity (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of immune response (ortholog); negative regulation of T cell activation (ortholog); PARTI CIPATES IN T cell receptor signaling pathway; ASSOCIATED WITH anti-basement membrane glomerulonephritis; Colorectal Neoplasms; periodontitis; FOUND IN external side of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; alpha-Zearalanol | 9 | 101866124 | 101879278 | Rat | 178 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 61887 | Pdcd2 | programmed cell death 2 | ENCODES a protein that exhibits enzyme binding (ortholog); protein carrier chaperone (ortholog); INVOLVED IN programmed cell death; regulation of hematopoietic progenitor cell differentiation (ortholog); ribosomal small subunit biogenesis (ortholog); FOUND IN cytosol (ortholog); nucleolus (ortholog) ; INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol | 1 | 65158034 | 65163524 | Rat | 99 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 620816 | Pdcd4 | programmed cell death 4 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN epithelial to mesenchymal transition involved in cardiac fibroblast development; negative regulation of apoptotic process; positive regulation of smooth muscle cell apoptotic process; PARTICIPATES IN mTOR signaling pathway; ASSOCIAT ED WITH Arterial Injury; Pulmonary Arterial Hypertension; Lung Neoplasms (ortholog); FOUND IN nucleus; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 1 | 262912659 | 262949581 | Rat | 304 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1310561 | Pdcd5 | programmed cell death 5 | ENCODES a protein that exhibits acetyltransferase activator activity (ortholog); beta-tubulin binding (ortholog); heparin binding (ortholog); INVOLVED IN cellular response to transforming growth factor beta stimulus (ortholog); negative regulation of protein folding (ortholog); positive regulation o f apoptotic process (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,4-dinitrotoluene | 1 | 97442755 | 97448084 | Rat | 104 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1311239 | Pdcd6 | programmed cell death 6 | ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to heat (ortholog); COPII vesicle coating (ortholog); FOUND IN COPII vesicle coat (ortholog) ; Cul3-RING ubiquitin ligase complex (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol | 1 | 30795105 | 30810771 | Rat | 203 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308961 | Pdcd7 | programmed cell death 7 | INVOLVED IN positive regulation of apoptotic signaling pathway (ortholog); positive regulation of T cell apoptotic process (ortholog); response to glucocorticoid (ortholog); FOUND IN spliceosomal complex (ortholog); U12-type spliceosomal complex (ortholog); U2AF complex (ortholog); INTERACTS WITH 2, 3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A | 8 | 74757768 | 74772495 | Rat | 63 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1559712 | Pdcl2 | phosducin-like 2 | INVOLVED IN acrosome assembly (ortholog); flagellated sperm motility (ortholog); sperm axoneme assembly (ortholog); ASSOCIATED WITH male infertility (ortholog); FOUND IN endoplasmic reticulum (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Cuprizon; trichloroethene | 14 | 32228776 | 32249467 | Rat | 23 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1309663 | Pdcl3 | phosducin-like 3 | ENCODES a protein that exhibits protein folding chaperone; vascular endothelial growth factor receptor 2 binding (ortholog); INVOLVED IN cellular response to heat; protein folding; actin cytoskeleton organization (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (o rtholog); INTERACTS WITH 2,6-dinitrotoluene; 2-methoxyethanol; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | 9 | 48730083 | 48738554 | Rat | 123 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1359329 | Pdcd10 | programmed cell death 10 | ENCODES a protein that exhibits protein homodimerization activity (ortholog); INVOLVED IN cellular response to anoxia; negative regulation of inflammatory response; positive regulation of mesenchymal cell apoptotic process; ASSOCIATED WITH Subarachnoid Hemorrhage; varicocele; arteriovenous malformat ions of the brain (ortholog); FOUND IN cell periphery; cytoplasm; Golgi apparatus; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 2 | 162602516 | 162644690 | Rat | 169 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1304933 | Pdcd11 | programmed cell death 11 | ENCODES a protein that exhibits NF-kappaB binding (ortholog); INVOLVED IN RNA processing (inferred); rRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog); nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodi benzodioxine; 2,4-dinitrotoluene | 1 | 255922198 | 255963336 | Rat | 102 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1589941 | Pdcd2l | programmed cell death 2-like | FOUND IN cytoplasm (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 1 | 95947476 | 95959738 | Rat | 57 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1564319 | Pdcd5l1 | programmed cell death 5 like 1 | ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN apoptotic process (inferred); INTERACTS WITH bisphenol A; Cuprizon; indole-3-methanol | 3 | 84051611 | 84053009 | Rat | 9 | symbol , PhenoGen | gene, protein-coding, PREDICTED [RefSeq] |
| 68357 | Pdcd6ip | programmed cell death 6 interacting protein | ENCODES a protein that exhibits SH3 domain binding; calcium-dependent protein binding (ortholog); protein dimerization activity (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); extracellular exosome biogenesis (ortholog); PARTICI PATES IN endocytosis pathway; ASSOCIATED WITH osteoarthritis (ortholog); primary autosomal recessive microcephaly 29 (ortholog); FOUND IN neuronal cell body; perinuclear region of cytoplasm; actomyosin (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 8 | 122469223 | 122524993 | Rat | 181 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1306403 | Pdcd1lg2 | programmed cell death 1 ligand 2 | ENCODES a protein that exhibits receptor ligand activity (ortholog); INVOLVED IN negative regulation of activated T cell proliferation (ortholog); negative regulation of interleukin-10 production (ortholog); negative regulation of T cell activation (ortholog); ASSOCIATED WITH Spinal Cord Injuries; a utoimmune hepatitis (ortholog); Coxsackievirus Infections (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; bisphenol A | 1 | 236572497 | 236637490 | Rat | 82 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1593001 | Pdcd6-ps1 | programmed cell death 6, pseudogene 1 | | X | 104026911 | 104027485 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 11415410 | Pdcd7-ps1 | programmed cell death 7, pseudogene 1 | | 11 | 50926484 | 50928851 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1584015 | Pdcl1-ps1 | phosducin-like 1, pseudogene 1 | | 3 | 41263570 | 41331087 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 2320082 | Pdcd6ip-ps1 | programmed cell death 6 interacting protein, pseudogene | | 11 | 57165900 | 57166600 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 620817 | Aifm1 | apoptosis inducing factor, mitochondria associated 1 | ENCODES a protein that exhibits DNA binding (ortholog); FAD binding (ortholog); NAD(P)H oxidase H2O2-forming activity (ortholog); INVOLVED IN cellular response to aldosterone; cellular response to estradiol stimulus; cellular response to hydrogen peroxide; PARTICIPATES IN ceramide signaling pathway; apoptotic cell death pathway; ASSOCIATED WITH Brain Hypoxia-Ischemia; Brain Injuries; Diabetic Cystopathy; FOUND IN cytoplasm (ortholog); cytosol (ortholog); mitochondrial intermembrane space (ortholog); INTERACTS WITH (+)-schisandrin B; (+)-sesamin; (Z)-3-butylidenephthalide | X | 132528107 | 132567237 | Rat | 516 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1566211 | Cd274 | CD274 molecule | ENCODES a protein that exhibits receptor ligand activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN positive regulation of cell migration; positive regulation of T cell proliferation; cell surface receptor signaling pathway (ortholog); ASSOCIATED WITH Corneal Graft Reject ion; Experimental Mammary Neoplasms; periodontitis; FOUND IN cell surface; early endosome membrane (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 1 | 236526215 | 236549956 | Rat | 314 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1561612 | Pgcka1 | PDCD10 and GCKIII kinases associated 1 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN regulation of cell cycle (ortholog); ASSOCIATED WITH cholestasis (ortholog); FOUND IN cell periphery (ortholog); INTERACTS WITH 17beta-estradiol (ortholog); 3-methylcholanthrene (ortholog); 4,4'-sulfonyldiphenol (ortholog) | 14 | 44740965 | 44832180 | Rat | 53 | old_gene_name , name | gene, protein-coding, VALIDATED [RefSeq] |