ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to UV (ortholog); negative regulation of inflammatory response (ortholog); negative regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH h
CRISPR-Cas9 technology was used to generate a PBK KO rat. Cas9 editing of exon 4 in the rat PBK gene resulted in the insertion of a single âTâ resulting in a frame shift and premature termination of the PBK