| 62014 | Nxf1 | nuclear RNA export factor 1 | ENCODES a protein that exhibits mRNA binding (ortholog); RNA binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); poly(A)+ mRNA export from nucleus (ortholog); RNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; influenz a A pathway; mRNA decay pathway; ASSOCIATED WITH intellectual disability (ortholog); FOUND IN cytoplasm (ortholog); nuclear inclusion body (ortholog); nuclear pore (ortholog); INTERACTS WITH 17beta-estradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 1 | 215084563 | 215097756 | Rat | 180 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1594679 | Alyref | Aly/REF export factor | ENCODES a protein that exhibits C5-methylcytidine-containing RNA reader activity (ortholog); molecular adaptor activity (ortholog); RNA binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); mRNA metabolic process (ortholog); RNA export from nucleus (ortholog); PARTICIPATES IN NXF1 yle='font-weight:700;'>NXF1-NXT1 export pathway; mRNA decay pathway; RNA transport pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); human immunodeficiency virus infectious disease (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); chromosome, telomeric region (ortholog); cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 10 | 106369750 | 106373395 | Rat | 135 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1593382 | Ddx19b | DEAD-box helicase 19B | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); PARTICIPATES IN NXF1-NXT1 export pathway; FOUND IN nuclear envelope (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotolu ene; 2,6-dinitrotoluene | 19 | 55877567 | 55910134 | Rat | 65 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 70923 | Ddx39b | DExD-box helicase 39B | ENCODES a protein that exhibits protein-containing complex binding; ATP hydrolysis activity (ortholog); ATP-dependent activity, acting on RNA (ortholog); INVOLVED IN liver development; positive regulation of cell growth involved in cardiac muscle cell development; positive regulation of DNA biosynth etic process; PARTICIPATES IN NXF1-NXT1 export pathway; spliceosome pathway; ASSOCIATED WITH type 1 diabetes mellitus (ortholog); FOUND IN nuclear matrix; protein-containing complex; cytoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 20 | 3577200 | 3589651 | Rat | 155 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1307329 | Gle1 | GLE1 RNA export mediator | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN mRNA export from nucleus (inferred); mRNA transport (inferred); poly(A)+ mRNA export from nucleus (inferred); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH Congenital A rthrogryposis with Anterior Horn Cell Disease (ortholog); genetic disease (ortholog); lethal congenital contracture syndrome 1 (ortholog); FOUND IN centriole (ortholog); centrosome (ortholog); ciliary basal body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; gentamycin; levetiracetam | 3 | 33607160 | 33638879 | Rat | 81 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1304977 | Nup214 | nucleoporin 214 | ENCODES a protein that exhibits nuclear localization sequence binding; nuclear export signal receptor activity (ortholog); structural constituent of nuclear pore (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); protein export from nucleus (ortholog); protein import into nucleus (ortholog ); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; mRNA nuclear export pathway; NXF1-NXT1 export pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); brain disease (ortholog); FOUND IN nuclear envelope; cytoplasmic side of nuclear pore (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; diethylstilbestrol | 3 | 35652841 | 35738323 | Rat | 110 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1309327 | Nxt1 | nuclear transport factor 2-like export factor 1 | ENCODES a protein that exhibits small GTPase binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); protein export from nucleus (ortholog); RNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; influenza A pathway; mRNA deca y pathway; FOUND IN cytosol (ortholog); nuclear pore (ortholog); nuclear RNA export factor complex (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 3 | 156562121 | 156565043 | Rat | 98 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305692 | Sarnp | SAP domain containing ribonucleoprotein | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; FOUND IN nuclear speck (ortholog); nucl eus (ortholog); transcription export complex (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil; benzo[a]pyrene | 7 | 1835597 | 1889833 | Rat | 93 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1308657 | Thoc1 | THO complex subunit 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN mRNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; RNA transport pathway; spliceosome pathway; ASSOCIATED WITH autosomal dominant nonsyndromic deafness 86 (ortholog); FOUND IN chromosome, telomeric region (ortholog); cytoplasm (ortholog); nuclear speck (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 18 | 1253041 | 1291956 | Rat | 103 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1561623 | Thoc2 | THO complex subunit 2 | ENCODES a protein that exhibits mRNA binding (ortholog); INVOLVED IN negative regulation of neuron projection development; blastocyst development (ortholog); cell morphogenesis (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; RNA transport pathway; spliceos ome pathway; ASSOCIATED WITH arthrogryposis multiplex congenita-7, X-linked (ortholog); genetic disease (ortholog); immunodeficiency 127 (ortholog); FOUND IN chromosome, telomeric region (ortholog); cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine | X | 125500549 | 125615139 | Rat | 142 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1304991 | Thoc5 | THO complex subunit 5 | ENCODES a protein that exhibits mRNA binding (ortholog); INVOLVED IN blastocyst development (ortholog); cell morphogenesis (ortholog); monocyte differentiation (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; RNA transport pathway; ASSOCIATED WITH anemia (o rtholog); breast carcinoma (ortholog); leukopenia (ortholog); FOUND IN chromosome, telomeric region (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 14 | 83982302 | 84016193 | Rat | 83 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 708553 | Thoc6 | THO complex subunit 6 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN central nervous system development (ortholog); mRNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; RNA transport pathway; ASSOCIATED WITH Beaulieu-Boycott-Innes Syndro me (ortholog); genetic disease (ortholog); FOUND IN chromosome, telomeric region (ortholog); nuclear speck (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A | 10 | 13204643 | 13210004 | Rat | 84 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1305475 | Thoc7 | THO complex subunit 7 | INVOLVED IN mRNA export from nucleus (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; RNA transport pathway; FOUND IN chromosome, telomeric region (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1,3-dinitrobenzene; bisphenol A; flutamid e | 15 | 13692855 | 13707692 | Rat | 76 | description | gene, protein-coding, VALIDATED [RefSeq] |