Nppc Gene Search Result

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5 records found for search term Nppc

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
620850	Nppc	natriuretic peptide C	ENCODES a protein that exhibits hormone activity; hormone receptor binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cGMP biosynthetic process; negative regulation of cell population proliferation; negative regulation of collagen biosynthetic process; PARTICIPATES IN C-type natr ... (more) iuretic peptide signaling pathway; ASSOCIATED WITH decreased body length; decreased body weight; decreased cranium length; ASSOCIATED WITH aortic valve stenosis; heart disease; Hypoxia; FOUND IN extracellular space; secretory granule; protein-containing complex (ortholog); INTERACTS WITH 3',5'-cyclic GMP; 6-propyl-2-thiouracil; acrylamide	9	94767986	94772186	Rat	228	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
127284866	Nppc^em1Kyo	natriuretic peptide C; ZFN induced mutant 1, Kyo	Selected ZFNs were designed to target exon 1 of rat Nppc, which encodes the N-terminus of natriuretic peptide precursor C (target sequence: CGAAGCCAAGCCCGGGACaccaccGAAGGTGGGTGCTGTCGCG; nucleotides 179 - 221, NC_005108.4). This allele ( delta 6) was deduced to ge ... (more) nerate a two a.a. deletion (a.a. 28 and 29, Pro and Pro, NP_446202, at nucleotides 198 - 203, NM_053750.1).				Rat		symbol , description	gene, allele
127284869	Nppc^em2Kyo	natriuretic peptide C; ZFN induced mutant 2 , Kyo	Selected ZFNs were designed to target exon 1 of rat Nppc, which encodes the N-terminus of natriuretic peptide precursor C (target sequence: CGAAGCCAAGCCCGGGACaccaccGAAGGTGGGTGCTGTCGCG; nucleotides 179 - 221, NC_005108.4). This allele ( delta 9) was deduced to ge ... (more) nerate one amino-acid substitution (a.a. 26, from Gly to Ala, NP_446202, at nucleotides 192 - 194, NM_053750.1) and a three amino-acid deletion (a.a. 27 - 29, Thr, Pro and Pro, NP_446202, at nucleotides 193 - 201, NM_053750.1), within the N-terminal portion of the full-length Nppc				Rat		symbol , description	gene, allele
127284871	Nppc^em3Kyo	natriuretic peptide C; ZFN induced mutant 3, Kyo	ASSOCIATED WITH decreased body length; decreased body weight; decreased cranium length				Rat	10	symbol , description	gene, allele
127284873	Nppc^em4Kyo	natriuretic peptide C; ZFN induced mutant 4, Kyo	ASSOCIATED WITH decreased body length; decreased body weight; decreased cranium length				Rat	8	symbol , description	gene, allele