ENCODES a protein that exhibits ubiquitin protein ligase activity; chromatin binding (ortholog); nuclear thyroid hormone receptor binding (ortholog); INVOLVED IN protein ubiquitination; axis elongation involved in somitogenesis (ortholog); embryonic brain development (ortholog); PARTICIPATES IN RNA
polymerase II transcription pathway; ASSOCIATED WITH adrenocortical carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); angiosarcoma (ortholog); FOUND IN ubiquitin ligase complex; CKM complex (ortholog); mediator complex (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine
ENCODES a protein that exhibits beta-catenin binding (inferred); transcription coregulator activity (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH Developmental Disease (ortholog); genetic