ENCODES a protein that exhibits GDP-mannose 4,6-dehydratase activity (ortholog); identical protein binding (ortholog); NADP+ binding (ortholog); INVOLVED IN 'de novo' GDP-L-fucose biosynthetic process (ortholog); GDP-mannose metabolic process (ortholog); Notch signaling pathway (ortholog); PARTICIPA
TES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH open-angle glaucoma (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil