| 1309109 | Ercc2 | ERCC excision repair 2, TFIIH core complex helicase subunit | ENCODES a protein that exhibits 5'-3' DNA helicase activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN embryonic organ development; response to hypoxia; apoptotic process (ortholog); PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repai r pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH asphyxia neonatorum; acoustic neuroma (ortholog); acquired immunodeficiency syndrome (ortholog); FOUND IN transcription factor TFIIH core complex; CAK-ERCC2 complex (ortholog); cytoplasm (ortholog); INTERACTS WITH 4,4'-sulfonyldiphenol; aflatoxin B1; bisphenol A | 1 | 88161342 | 88175102 | Rat | 318 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 69419 | Ccnh | cyclin H | ENCODES a protein that exhibits kinase activity (ortholog); RNA polymerase II general transcription initiation factor activity (ortholog); INVOLVED IN protein stabilization (ortholog); regulation of G1/S transition of mitotic cell cycle (ortholog); regulation of transcription by RNA polymerase II (o rtholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; cell cycle pathway, mitotic; nucleotide excision repair pathway; ASSOCIATED WITH Experimental Mammary Neoplasms; Spinal Cord Injuries; transient cerebral ischemia; FOUND IN CAK-ERCC2 complex (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 2 | 17570449 | 17591078 | Rat | 134 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 621124 | Cdk7 | cyclin-dependent kinase 7 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase activity; protein-containing complex binding; ATP-dependent activity, acting on DNA (ortholog); INVOLVED IN protein phosphorylation; transcription by RNA polymerase II; positive regulation of meiotic cell cycle process involved in oocyte maturation (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; RNA polymerase II transcription pathway; cell cycle pathway, mitotic; ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN transcription factor TFIIH holo complex; CAK-ERCC2 complex (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; dibutyl phthalate | 2 | 33574623 | 33599485 | Rat | 219 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 628874 | Mnat1 | MNAT1 component of CDK activating kinase | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase activator activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); INVOLVED IN G1/S transition of mitotic cell cycle; negative regulation of apoptotic process; positive regulation of smooth muscle cell proliferation; PARTICIPATES IN RNA polymerase II transcription initiation pathway; nucleotide excision repair pathway; FOUND IN CAK-ERCC2 complex (ortholog); chromosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; aflatoxin B1 | 6 | 97550566 | 97706598 | Rat | 105 | description | gene, protein-coding, PROVISIONAL [RefSeq] |