| 1591983 | C4b | complement C4B | ENCODES a protein that exhibits antigen binding (ortholog); carbohydrate binding (ortholog); complement binding (ortholog); INVOLVED IN complement activation (ortholog); complement activation, classical pathway (ortholog); complement activation, GZMK pathway (ortholog); PARTICIPATES IN coagulation c ascade pathway; complement system pathway; Staphylococcus aureus infection pathway; ASSOCIATED WITH autistic disorder (ortholog); autoimmune disease (ortholog); complement component 4B deficiency (ortholog); FOUND IN extracellular region; extracellular space; axon (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate | 20 | 4201979 | 4216292 | Rat | 214 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 620005 | C4a | complement C4A (Rodgers blood group) | ENCODES a protein that exhibits antigen binding (ortholog); complement component C1q complex binding (ortholog); INVOLVED IN complement activation (ortholog); complement activation, classical pathway (ortholog); complement activation, GZMK pathway (ortholog); PARTICIPATES IN classical complement pat hway; ASSOCIATED WITH complement component 4A deficiency (ortholog); genetic disease (ortholog); Graves' disease (ortholog); FOUND IN extracellular region; extracellular space; axon (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 4010306 | 4024707 | Rat | 140 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 2399 | Cr1l | complement C3b/C4b receptor 1 like | INVOLVED IN negative regulation of complement activation; cellular response to hypoxia (ortholog); complement activation (ortholog); PARTICIPATES IN coagulation cascade pathway; complement system pathway; FOUND IN basolateral plasma membrane (ortholog); cell surface (ortholog); external side of plas ma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 2-nitrofluorene | 13 | 109138132 | 109189068 | Rat | 100 | name | gene, protein-coding, REVIEWED [RefSeq] |
| 620429 | Cfi | complement factor I | ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); peptidase activity (inferred); INVOLVED IN cellular response to interleukin-6; complement activation (ortholog); proteolysis (ortholog); PARTICIPATES IN coagulation cascade pathway; complement system pathway ; Staphylococcus aureus infection pathway; ASSOCIATED WITH Hearing Loss, Noise-Induced; age related macular degeneration 13 (ortholog); atypical hemolytic-uremic syndrome (ortholog); FOUND IN extracellular space; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 2 | 221062206 | 221104790 | Rat | 210 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2236 | C4bpb | complement component 4 binding protein, beta | INVOLVED IN negative regulation of complement activation, classical pathway (ortholog); positive regulation of protein catabolic process (ortholog); regulation of opsonization (ortholog); PARTICIPATES IN forkhead class A signaling pathway; coagulation cascade pathway; complement system pathway; ASSO CIATED WITH COVID-19 (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 13 | 44673064 | 44683781 | Rat | 92 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 2235 | C4bpa | complement component 4 binding protein, alpha | ENCODES a protein that exhibits complement binding (inferred); INVOLVED IN binding of sperm to zona pellucida (ortholog); negative regulation of complement activation, classical pathway (ortholog); positive regulation of protein catabolic process (ortholog); PARTICIPATES IN coagulation cascade pathw ay; complement system pathway; ASSOCIATED WITH COVID-19 (ortholog); Radiation Pneumonitis (ortholog); FOUND IN acrosomal matrix (ortholog); acrosomal vesicle (ortholog); cell body (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 13 | 44627959 | 44663552 | Rat | 138 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |