ENCODES a protein that exhibits signaling receptor activity (ortholog); vasopressin receptor activity (ortholog); INVOLVED IN negative regulation of urine volume; positive regulation of blood pressure; positive regulation of cell population proliferation; PARTICIPATES IN vasopressin signaling pathwa
y; vasopressin signaling pathway via receptor type 2; G protein mediated signaling pathway via Galphas family; ASSOCIATED WITH hypertension; ureteral obstruction; cardiomyopathy (ortholog); FOUND IN endocytic vesicle (ortholog); endosome (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bis(2-ethylhexyl) phthalate
CRISPR/Cas9 system was used to introduce a mutation in the Avpr2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 30-bp deletion in exon 2.
CRISPR/Cas9 system was used to introduce a mutation in the Avpr2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 9-bp deletion in exon 2.