ENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein-membrane adaptor activity (ortholog); INVOLVED IN dendrite arborization; negative regulation of dendrite extension; autophagosome assembly (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATE
D WITH Cardiomegaly; Crohn's disease (ortholog); inflammatory bowel disease (ortholog); FOUND IN glutamatergic synapse; synapse; Atg12-Atg5-Atg16 complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene
autophagy related 16-like 1; CRISPR/Cas9 induced mutant 8, RRRC
CRISPR-Cas9-mediated knock-in of a single base pair polymorphism of guanine to alanine in exon 10, resulting in a threonine to alanine substitution at amino acid position 299 in the rat. Mimics the same nucleotide substitution for the threonine to alanine substitution at amino acid position 300 in h