| 2047 | Adm | adrenomedullin | ENCODES a protein that exhibits adrenomedullin receptor binding; hormone activity (ortholog); receptor ligand activity (ortholog); INVOLVED IN androgen metabolic process; animal organ regeneration; cellular response to xenobiotic stimulus; PARTICIPATES IN p38 MAPK signaling pathway; hypoxia inducibl e factor pathway; ASSOCIATED WITH Acidoses; Cardiac Arrhythmias; congestive heart failure; FOUND IN extracellular space; cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-hydroxy-5alpha-androstan-3-one | 1 | 174164178 | 174182372 | Rat | 466 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 626469800 | Admem1Soar | adrenomedullin; CRISPR/Cas9 induced mutant 1, Soar | Crispr/Cas9 mediated 206 bp deletion associated with Exon 2 and the second intron of the Adm gene | | | | Rat | | symbol , description | gene, allele |
| 1302971 | Adm2 | adrenomedullin 2 | ENCODES a protein that exhibits hormone activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway; feeding behavior; negative regulation of blood pressure; ASSOCIATED WITH Myocardial Ischemia (ortholog); phlebitis (ortholog); vascular disease (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; (S)-nicotine; 17beta-estradiol | 7 | 122272808 | 122274594 | Rat | 108 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 12880383 | Kcna1Adms | potassium voltage-gated channel subfamily A member 1;autosomal dominant myokymia and seizures | ASSOCIATED WITH convulsive seizures; environmentally induced seizures; ASSOCIATED WITH epilepsy with generalized tonic-clonic seizures; episodic ataxia type 1; Myokymia | | | | Rat | 5 | symbol , old_gene_symbol | gene, allele |
| 61903 | Ackr5 | atypical chemokine receptor 5 | ENCODES a protein that exhibits adrenomedullin receptor activity; C-C chemokine binding (ortholog); C-X-C chemokine binding (ortholog); INVOLVED IN response to hypoxia; ASSOCIATED WITH abnormal vasodilation; ASSOCIATED WITH pulmonary hypertension; hepatocellular carcinoma (ortholog); FOUND IN endoso me (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; all-trans-retinoic acid | 7 | 65471254 | 65474110 | Rat | 77 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 628852 | Cacna1b | calcium voltage-gated channel subunit alpha1 B | ENCODES a protein that exhibits high voltage-gated calcium channel activity; protein phosphatase 2A binding; voltage-gated calcium channel activity; INVOLVED IN calcium ion import; calcium ion transport; optic nerve development; PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated sig naling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Experimental Autoimmune Encephalomyelitis; Hyperalgesia; brain edema (ortholog); FOUND IN axon terminus; dendritic shaft; glutamatergic synapse; INTERACTS WITH 1,2-dimethylhydrazine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil | 3 | 27779133 | 27944292 | Rat | 194 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 735204 | Panx1 | Pannexin 1 | ENCODES a protein that exhibits gap junction channel activity; gap junction hemi-channel activity; protease binding; INVOLVED IN cell-cell signaling; ATP transport (ortholog); calcium ion transport (ortholog); PARTICIPATES IN neuron-to-neuron signaling pathway via the electrical synapse; ASSOCIATED WITH autosomal recessive polycystic kidney disease; Acute Liver Failure (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN plasma membrane; protein-containing complex; bleb (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; atrazine | 8 | 20128783 | 20171200 | Rat | 179 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
| 1565449 | Parn | poly(A)-specific ribonuclease | ENCODES a protein that exhibits cation binding (ortholog); poly(A)-specific ribonuclease activity (ortholog); protein kinase binding (ortholog); INVOLVED IN box H/ACA sno(s)RNA 3'-end processing (ortholog); lncRNA processing (ortholog); miRNA catabolic process (ortholog); PARTICIPATES IN RNA degrada tion pathway; ASSOCIATED WITH autosomal recessive dyskeratosis congenita 6 (ortholog); dyskeratosis congenita (ortholog); genetic disease (ortholog); FOUND IN glutamatergic synapse; postsynapse; nuclear speck (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A | 10 | 1917830 | 2055749 | Rat | 124 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 3317 | Pgr | progesterone receptor | ENCODES a protein that exhibits hormone binding; nuclear steroid receptor activity; sequence-specific DNA binding; INVOLVED IN cellular response to estrogen stimulus; cellular response to follicle-stimulating hormone stimulus; cellular response to gonadotropin stimulus; PARTICIPATES IN phosphatidyli nositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH Brain Injuries; endometriosis; polycystic ovary syndrome; FOUND IN axon; axon terminus; dendrite; INTERACTS WITH (S)-naringenin; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | 8 | 14354398 | 14413271 | Rat | 851 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 628822 | Stab2 | stabilin 2 | ENCODES a protein that exhibits hyaluronic acid binding; cargo receptor activity (ortholog); low-density lipoprotein particle binding (ortholog); INVOLVED IN endocytosis; defense response to bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); Prostatic Neoplasms (ortholog); FOUND IN external side of plasma membrane; cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2-dimethylhydrazine; 17beta-estradiol | 7 | 23136938 | 23342633 | Rat | 103 | GenBank Protein | gene, protein-coding, VALIDATED [RefSeq] |
| 1306044 | Usp13 | ubiquitin specific peptidase 13 | ENCODES a protein that exhibits BAT3 complex binding (ortholog); cysteine-type deubiquitinase activity (ortholog); cysteine-type endopeptidase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); maintenance of unfolded protein (ortholog); positive regulation of ERAD pathway (o rtholog); ASSOCIATED WITH Arsenic Poisoning (ortholog); skin disease (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH (+)-schisandrin B; aconitine; acrylamide | 2 | 117502811 | 117617049 | Rat | 123 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1302955 | Ddah2 | DDAH family member 2, ADMA-independent | ENCODES a protein that exhibits dimethylargininase activity (ortholog); INVOLVED IN positive regulation of nitric oxide biosynthetic process (inferred); ASSOCIATED WITH coronary artery disease (ortholog); pre-eclampsia (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestr adiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 20 | 3766115 | 3769161 | Rat | 140 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 68438 | Oprl1 | opioid related nociceptin receptor 1 | ENCODES a protein that exhibits G protein-coupled receptor activity (ortholog); nociceptin receptor activity (ortholog); INVOLVED IN behavioral response to cocaine; behavioral response to ethanol; behavioral response to nicotine; ASSOCIATED WITH abnormal behavioral response to nicotine; abnormal coc aine self-administration; abnormal drug-induced reinstatement of an extinguished operant behavior for a drug reinforcer; ASSOCIATED WITH alcohol dependence; alcohol use disorder; Anorexia; FOUND IN plasma membrane (ortholog); synaptic membrane (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 3 | 189209495 | 189225406 | Rat | 190 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 13792571 | Oprl1m1Hubr | opioid related nociceptin receptor 1; ENU induced mutant1, Hubr | ASSOCIATED WITH abnormal behavioral response to nicotine; abnormal cocaine self-administration; abnormal drug-induced reinstatement of an extinguished operant behavior for a drug reinforcer; ASSOCIATED WITH alcohol dependence; cocaine dependence; heroin dependen ce | | | | Rat | 17 | description | gene, allele |
| 3714 | Slc6a4 | solute carrier family 6 member 4 | ENCODES a protein that exhibits actin filament binding; cocaine binding; identical protein binding; INVOLVED IN behavioral response to cocaine; cellular response to cGMP; cellular response to retinoic acid; PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; bu prenorphine pharmacodynamics pathway; ASSOCIATED WITH abnormal acquisiton of operant behavior for a cocaine reinforcer; abnormal cocaine self-administration; abnormal hemostasis; ASSOCIATED WITH anxiety disorder; borna disease; Burns; FOUND IN endomembrane system; plasma membrane; postsynaptic membrane; INTERACTS WITH (S)-amphetamine; 1,2-dimethylhydrazine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine | 10 | 62322688 | 62357060 | Rat | 557 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 14390068 | Slc6a4m1Hubr | solute carrier family 6 member 4; ZFN induced mutant1, Hubr | ASSOCIATED WITH abnormal acquisiton of operant behavior for a cocaine reinforcer; abnormal cocaine self-administration; anhedonia; ASSOCIATED WITH anxiety disorder; depressive disorder | | | | Rat | 11 | description | gene, allele |