| 2022 | Acp5 | acid phosphatase 5, tartrate resistant | ENCODES a protein that exhibits acid phosphatase activity; hydrolase activity; ferric iron binding (ortholog); INVOLVED IN bone resorption; cellular response to zinc ion starvation; multicellular organismal response to stress; PARTICIPATES IN rheumatoid arthritis pathway; riboflavin metabolic pathwa y; ASSOCIATED WITH Alveolar Bone Loss; Experimental Diabetes Mellitus; Postmenopausal Osteoporosis; FOUND IN extracellular space; lysosome (ortholog); INTERACTS WITH (20S)-ginsenoside Rg3; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate | 8 | 28939984 | 28946639 | Rat | 295 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 621239 | Mt-atp6 | mitochondrially encoded ATP synthase membrane subunit 6 | ENCODES a protein that exhibits proton channel activity (ortholog); proton-transporting ATP synthase activity, rotational mechanism (ortholog); INVOLVED IN response to hyperoxia; proton motive force-driven ATP synthesis (ortholog); proton motive force-driven mitochondrial ATP synthesis (ortholog); P ARTICIPATES IN electron transport chain pathway; ASSOCIATED WITH Reperfusion Injury; adult-onset ataxia and polyneuropathy (ortholog); Ataxia (ortholog); FOUND IN mitochondrion (ortholog); proton-transporting ATP synthase complex (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | MT | 7919 | 8599 | Rat | 190 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621872 | Mt-co2 | mitochondrially encoded cytochrome c oxidase II | ENCODES a protein that exhibits cytochrome-c oxidase activity (ortholog); INVOLVED IN lactation; response to ethanol; response to hypoxia; ASSOCIATED WITH acute myocardial infarction; Binge Drinking; Brain Injuries; FOUND IN mitochondrial inner membrane (ortholog); mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | MT | 7006 | 7689 | Rat | 228 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 621873 | Mt-co3 | mitochondrially encoded cytochrome c oxidase III | ENCODES a protein that exhibits cytochrome-c oxidase activity (inferred); electron transfer activity (inferred); INVOLVED IN respiratory chain complex IV assembly (ortholog); ASSOCIATED WITH cerebellar ataxia (ortholog); cytochrome-c oxidase deficiency disease (ortholog); epilepsy (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrial membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1 | MT | 8599 | 9382 | Rat | 143 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620081 | Mt-cyb | mitochondrially encoded cytochrome b | ENCODES a protein that exhibits protein-containing complex binding; quinol-cytochrome-c reductase activity (ortholog); INVOLVED IN animal organ regeneration; electron transport coupled proton transport; response to cadmium ion; ASSOCIATED WITH Burns; Experimental Diabetes Mellitus; Experimental Live r Cirrhosis; FOUND IN mitochondrial inner membrane; protein-containing complex; mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | MT | 14136 | 15278 | Rat | 194 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620555 | Mt-nd1 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN response to hydroperoxide; response to hypoxia; response to xenobiotic stimulus; ASSOCIATED WITH Hypoxia; type 2 diabetes mellitus; Alzheimer's disease (ortholog); FOUND IN dendrite; neuronal cell body; mitochondrial inner membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; acetamiprid | MT | 2740 | 3694 | Rat | 224 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620556 | Mt-nd2 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 | ENCODES a protein that exhibits ionotropic glutamate receptor binding; protein kinase binding; NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN response to hypoxia; mitochondrial electron transport, NADH to ubiquinone (ortholog); mitochondrial respiratory chain complex I assembly (or tholog); ASSOCIATED WITH Hypoxia; epilepsy (ortholog); Leber hereditary optic neuropathy (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamiprid | MT | 3904 | 4942 | Rat | 132 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620557 | Mt-nd3 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN cellular response to glucocorticoid stimulus; response to hormone; response to light intensity; ASSOCIATED WITH Huntington's disease; hypothyroidism; Parkinson's disease; FOUND IN mitochondrial inner mem brane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; atrazine | MT | 9451 | 9798 | Rat | 115 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620559 | Mt-nd4 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN cerebellum development; in utero embryonic development; response to ethanol; ASSOCIATED WITH Alzheimer's disease (ortholog); Developmental Disabilities (ortholog); dilated cardiomyopathy (ortholog); FOUN D IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | MT | 10160 | 11537 | Rat | 149 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620494 | Mt-nd4l | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN ATP synthesis coupled electron transport (inferred); proton transmembrane transport (inferred); respiratory electron transport chain (inferred); ASSOCIATED WITH colorectal cancer (ortholog); diabetes mel litus (ortholog); dilated cardiomyopathy (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | MT | 9870 | 10166 | Rat | 95 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620560 | Mt-nd5 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN response to hydrogen peroxide; response to hypoxia; mitochondrial electron transport, NADH to ubiquinone (ortholog); ASSOCIATED WITH hepatocellular carcinoma; Hearing Loss (ortholog); Leber congenital am aurosis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | MT | 11736 | 13565 | Rat | 161 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |
| 620561 | Mt-nd6 | mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN response to cocaine; response to hydrogen peroxide; response to nicotine; ASSOCIATED WITH Chemical and Drug Induced Liver Injury; acute megakaryocytic leukemia (ortholog); autism spectrum disorder (ortho log); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A | MT | 13543 | 14061 | Rat | 163 | GenBank Protein | gene, protein-coding, PROVISIONAL [RefSeq] |