| 619951 | Abcb1a | ATP binding cassette subfamily B member 1A | ENCODES a protein that exhibits ABC-type xenobiotic transporter activity (ortholog); ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN cellular hyperosmotic salinity response; cellular response to alkaloid; cellular response to antibiotic; PARTICIPATES IN axitinib pharmacokinet ics pathway; clopidogrel pharmacodynamics pathway; clopidogrel pharmacokinetics pathway; ASSOCIATED WITH abnormal blood-brain barrier function; abnormal intestinal absorption; abnormal xenobiotic pharmacokinetics; ASSOCIATED WITH Audiogenic Epilepsy; encephalitis; end stage renal disease; FOUND IN apical part of cell; apical plasma membrane; brush border membrane; INTERACTS WITH (+)-isoborneol; (+)-pilocarpine; (+)-schisandrin B | 4 | 26312403 | 26488456 | Rat | 1844 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12904058 | Abcb1aem1Sage | ATP binding cassette subfamily B member 1A; ZFN induced mutant 1, Sage | ASSOCIATED WITH abnormal xenobiotic pharmacokinetics | | | | Rat | 2 | symbol , old_gene_name , old_gene_symbol | gene, allele |
| 12907569 | Abcb1aem2Sage | ATP binding cassette subfamily B member 1A; ZFN induced mutant 2, Sage | ASSOCIATED WITH abnormal blood-brain barrier function; abnormal intestinal absorption | | | | Rat | 2 | symbol , old_gene_symbol | gene, allele |
| 12907571 | Abcb1aem3Sage | ATP binding cassette subfamily B member 1A; ZFN induced mutant 3, Sage) | The ZFN-induced mutant allele contains one 19- bp deletion and one 428-bp deletion within Abcba1 gene. The homozygous knockout rats display total loss of protein via Western blot. | | | | Rat | | symbol , old_gene_symbol | gene, allele |
| 3318 | Abcb1b | ATP-binding cassette, sub-family B member 1B | ENCODES a protein that exhibits floppase activity (ortholog); INVOLVED IN cellular response to external biotic stimulus; cellular response to tumor necrosis factor; establishment of endothelial blood-brain barrier; PARTICIPATES IN bile acid transport pathway; ASSOCIATED WITH brain ischemia; cholesta sis; colorectal adenocarcinoma; FOUND IN apical plasma membrane; external side of apical plasma membrane; Golgi membrane; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; 1,2-dimethylhydrazine | 4 | 26197706 | 26280156 | Rat | 390 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 620248 | Abcb4 | ATP binding cassette subfamily B member 4 | ENCODES a protein that exhibits ATPase-coupled transmembrane transporter activity (ortholog); ceramide floppase activity (ortholog); phosphatidylcholine floppase activity (ortholog); INVOLVED IN response to glucocorticoid; response to xenobiotic stimulus; bile acid secretion (ortholog); PARTICIPATES IN multidrug resistance protein mediated transport pathway; bile acid transport pathway; ASSOCIATED WITH cholestasis; Experimental Diabetes Mellitus; Animal Disease Models (ortholog); FOUND IN apical plasma membrane; Golgi membrane; cytoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 1,9-dideoxyforskolin; 1-naphthyl isothiocyanate | 4 | 26106895 | 26164440 | Rat | 467 | ensembl_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |