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Strain Registration

Strain: ZDF-Leprm1Rll

Symbol: ZDF-Leprm1Rll
Strain: ZDF-Leprm1
Substrain: Rll
RGD ID: 9835401
Citation ID: RRID:RGD_9835401
Ontology ID: RS:0003867
Alleles: Leprm1Rll
Also Known As: ZDF/Vc; ZDF-Leprm1Rll; ZDF-Lepr^[m1Rll]
Type: mutant
Available Source: Not Available
Origination: Laboratory of Human Behavior and Metabolism, Rockefeller University, New York
Description: The Zucker rats from Charles River (ZDF-Leprfa/Crl) carry the Leprm1Rll allele that has substitution of a nucleotide at 880 (A-C) results in Gln-Pro at position 269
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25116,294,409 - 116,477,904RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05120,503,475 - 120,682,281RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05124,380,327 - 124,556,585RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45122,320,075 - 122,503,449RGD_MAPPER_PIPELINERGSC3.4






References

References - curated
# Reference Title Reference Citation
1. Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr). Chua SC Jr, etal., Diabetes. 1996 Aug;45(8):1141-3.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Similar mutation was observed in ZDF/Vc bred at Vassar College 9835399

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 ZDF-Leprm1Rll    ZDF-Leprm1Rll    Symbol updated 68687 APPROVED
2016-03-16 ZDF-Leprm1Rll    ZDF-Leprm1Rll    Name updated 68913 APPROVED
2016-03-16 ZDF-Leprm1Rll    ZDF-Leprm1Rll    Symbol updated 68687 APPROVED
2016-03-16 ZDF-Leprm1Rll    ZDF-Leprm1Rll    Name updated 68913 APPROVED
2015-03-24 ZDF-Leprm1Rll    ZUC-Leprm1Rll    Symbol updated 68687 APPROVED
2015-03-24 ZDF-Leprm1Rll    ZUC-Leprm1Rll    Name updated 68913 APPROVED
2015-03-24 ZDF-Leprm1Rll    ZUC-Leprm1Rll    Symbol updated 68687 APPROVED
2015-03-24 ZDF-Leprm1Rll    ZUC-Leprm1Rll    Name updated 68913 APPROVED