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Strain: Y59/Zgd

Symbol: Y59/Zgd
Strain: Y59
Substrain: Zgd
RGD ID: 9831158
Citation ID: RRID:RGD_9831158
Ontology ID: RS:0003865
Type: inbred
Available Source: Not Available
Origination: University of Zagreb, Republic of Croatia
Description: Strain developed by Prof. Borislav Nakic, Prof. Silobrcic and Prof. Andrija Kastelan from outbred Wistar rats during 1960s, maintained at Department of Animal Physiology,Faculty of Science, University of Zagreb, Republic of Croatia
Inbred Generations: F80+
Last Known Status: Live Animals (as of 2020-10-05)
Research Usage Immunology and transplantational research





References

References - curated
# Reference Title Reference Citation
1. Absence of Cd36 mutation in the original spontaneously hypertensive rats with insulin resistance. Gotoda T, etal., Nat Genet 1999 Jul;22(3):226-8.
2. Role of flavonoids on oxidative stress and mineral contents in the retinoic acid-induced bone loss model of rat. Orsolic N, etal., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23.
3. Data registered by Dr. Djikic Personal communication between Dr. Djikic's group and the RGD curators.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics good health, quick growth rate, large number of pups, good maternal care and docile nature 9831159
strain_life_disease decreased bone mineral density was noticed in rats given 80 mg/kg body weight of retinoic acid orally for 2 weeks daily 9831160
strain_life_disease dietary flavonoids reduce retinoic acid-induced oxidative stress and bone loss 9831160

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-02-27 Y59/Zgd    Y59/Zgd    Name updated 68913 APPROVED
2015-02-27 Y59/Zgd    Y59/Zgd    Name updated 68913 APPROVED