Strain Report - Rat Genome Database

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Strain: SS.MNS-(D2Chm366-D2Rat52)/Ayd

Symbol: SS.MNS-(D2Chm366-D2Rat52)/Ayd
Strain: SS.MNS-(D2Chm366-D2Rat52)
Substrain: Ayd
RGD ID: 7421654
Citation ID: RRID:RGD_7421654
Ontology ID: RS:0003597
Also Known As: C2S.M24; DSS.MNS-(D2Chm366-D2Rat52)/Lt; SS.MNS-(D2Chm366-D2Rat52)/Ayd
Type: congenic
Available Source: Not Available
Origination: Centre Hospitalier de Universite de Montreal (CRCHUM), Quebec, Canada
Description: Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous rat was then backcrossed to SS/Jr rat to duplicate the fragment.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22193,094,852 - 193,094,998RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.02208,081,050 - 208,081,195RGD_MAPPER_PIPELINERnor6.0
Rnor_5.02227,502,003 - 227,502,148RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.42200,866,667 - 200,866,813RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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Clinical Measurement
mean arterial blood pressure

References

References - curated
# Reference Title Reference Citation
1. Cardiac pathways distinguish two epistatic modules enacting BP quantitative trait loci and candidate gene analysis. Chauvet C, etal., Hypertens Res. 2009 Jul;32(7):631-7. doi: 10.1038/hr.2009.70. Epub 2009 May 22.
2. Combining distinctive and novel loci doubles BP reduction, reverses diastolic dysfunction and mitigates LV hypertrophy. Crespo K, etal., J Hypertens. 2013 May;31(5):927-35. doi: 10.1097/HJH.0b013e32835edc7e.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 2 / 1 (D2Rat52)
Rat AssemblyChrPosition (strand)Source
mRatBN7.22193,094,852 - 193,094,998 (+)MAPPER
Rnor_6.02208,081,050 - 208,081,195NCBI
Rnor_5.02227,502,003 - 227,502,148UniSTS
RGSC_v3.42200,866,667 - 200,866,813RGD
RGSC_v3.42200,866,668 - 200,866,813UniSTS
RGSC_v3.12200,829,422 - 200,829,567RGD
Celera2185,557,445 - 185,557,622UniSTS
RH 3.4 Map21366.3RGD
RH 3.4 Map21366.3UniSTS
RH 2.0 Map21028.7RGD
SHRSP x BN Map273.4398RGD
Cytogenetic Map2q34UniSTS
Strain QTL Data
Symbol Name Trait
Bp366 Blood pressure QTL 366 arterial blood pressure trait   (VT:2000000)    

Additional Information