Strain Report - Rat Genome Database

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Strain: SS.MNS-(D2Chm254-D2Chm161)/Ayd

Symbol: SS.MNS-(D2Chm254-D2Chm161)/Ayd
Strain: SS.MNS-(D2Chm254-D2Chm161)
Substrain: Ayd
RGD ID: 7421643
Citation ID: RRID:RGD_7421643
Ontology ID: RS:0003592
Also Known As: C2S.M18; DSS.MNS-(D2Chm254-D2Chm161)/Lt; SS.MNS-(D2Chm254-D2Chm161)/Ayd
Type: congenic
Available Source: Not Available
Origination: Centre Hospitalier de Universite de Montreal (CRCHUM), Quebec, Canada
Description: Congenic substrain created by backcrossing congenic strain SS.MNS-(D2Chm25-D2Mit14)/Ayd strain into the parental Dahl Salt-sensitive (SS/Jr) strain, the F2 rats were genotyped with markers that resided in the region of interest, heterozygous rat was then backcrossed to SS/Jr rat to duplicate the fragment.
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View
Hypotension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table

Clinical Measurement
mean arterial blood pressure

References

References - curated
# Reference Title Reference Citation
1. Cardiac pathways distinguish two epistatic modules enacting BP quantitative trait loci and candidate gene analysis. Chauvet C, etal., Hypertens Res. 2009 Jul;32(7):631-7. doi: 10.1038/hr.2009.70. Epub 2009 May 22.
2. Combining distinctive and novel loci doubles BP reduction, reverses diastolic dysfunction and mitigates LV hypertrophy. Crespo K, etal., J Hypertens. 2013 May;31(5):927-35. doi: 10.1097/HJH.0b013e32835edc7e.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Bp364 Blood pressure QTL 364 arterial blood pressure trait   (VT:2000000)    

Additional Information