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Strain Registration

Strain: AGUS

Symbol: AGUS
Strain: AGUS
RGD ID: 70425
Citation ID: RRID:RGD_70425
Ontology ID: RS:0000037
Type: inbred
Available Source: Not Available
Description: Germ-free strain developed by Gustafsson from stock (Sprague-Dawley?) by hysterectomy derivation in 1948 at F10. To Laboratory Animals Centre, Carshalton 1968 at F26.
Genetic Markers: a, c, H
Coat Color: Albino
Inbred Generations: F>35
Last Known Status: Unknown

Substrains
AGUS/OlaHsd






References

References - curated
# Reference Title Reference Citation
1. Inbred Strains Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press
2. Rat Strain List M. Festing Rat Strain List
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Susceptible to experimental allergic encephalitis (Hughes and Stedronska 1973). Relatively resistant to infection by Entamoeba histolytica (Neal and Harris 1975). Good breeding performance, although sensitive to environmental influences. About 1-4% tailless young, which are infertile with major skeletal and genital defects (Lovell and Sparrow 1984). Long gestation period (3/8) (Peters 1986). Absence of a microflora in germfree AGUS rats prolongs the cell cycle time and reduces proliferative activity in the colonic crypts (Alam et al 1994). 1004
strain_characteristics Susceptible to experimental allergic encephalitis (Hughes and Stedronska 1973). Relatively resistant to infection by Entamoeba histolytica (Neal and Harris 1975). Good breeding performance, although sensitive to environmental influences. About 1-4% tailless young, which are infertile with major skeletal and genital defects (Lovell and Sparrow 1984). Long gestation period (3/8) (Peters 1986). Absence of a microflora in germfree AGUS rats prolongs the cell cycle time and reduces proliferative activity in the colonic crypts (Alam et al 1994). 634612