Bogden in the mid-1970s from Noble (Nb) strain rats (brother x sister mated but not descended from a single pair, and therefore not necessarily isogenic). To Fredrich Cancer Research facility in 1978. Note that the strain name NBL was selected in 1989. In the literature these rats are called Noble or Nb rats, usually without identifying whether the animals came from the non-isogenic colony of Dr. Noble or from the isogenic colony at the National Cancer Institute (Greenhouse et al 1990).
Good reproductive performance. Hyperplasia and dysplasia of the dorsolateral prostate causedby implantation of testosterone and estradiol-17/-filled silastic capsules. Prolonged implantationleads to prostatic carcinoma (Leav et al 1988, 1989).
Good reproductive performance. Hyperplasia and dysplasia of the dorsolateral prostate causedby implantation of testosterone and estradiol-17/-filled silastic capsules. Prolonged implantationleads to prostatic carcinoma (Leav et al 1988, 1989).