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Strain Registration

Strain: NAft:HS

Symbol: NAft:HS
Strain: HS
Substrain: NAft
Full Name: Heterogeneous stock
RGD ID: 6480190
Citation ID: RRID:RGD_6480190
Ontology ID: RS:0003205
Type: outbred
Available Source: Not Available
Origination: Psychiatry and Forensic Medicine, Institute of Neurosciences, School of Medicine, Autonomous University of Barcelona, Barcelona, Spain
Description: From Dr. Eva Redei, Center for Comparative Medicine, Northwestern University to Dr. Alberto Fernandez-Teruel, Barcelona
Last Known Status: Unknown





References

References - curated
# Reference Title Reference Citation
1. Heterogeneous stock rat: a unique animal model for mapping genes influencing bone fragility. Alam I, etal., Bone. 2011 May 1;48(5):1169-77. Epub 2011 Feb 18.
2. Fine mapping of bone structure and strength QTLs in heterogeneous stock rat. Alam I, etal., Bone. 2015 Dec;81:417-26. doi: 10.1016/j.bone.2015.08.013. Epub 2015 Aug 19.
3. Gene expression in amygdala as a function of differential trait anxiety levels in genetically heterogeneous NIH-HS rats. Diaz-Moran S, etal., Behav Brain Res. 2013 Sep 1;252:422-31. doi: 10.1016/j.bbr.2013.05.066. Epub 2013 Jun 15.
4. Effects of environmental and physiological covariates on sex differences in unconditioned and conditioned anxiety and fear in a large sample of genetically heterogeneous (N/Nih-HS) rats. Lopez-Aumatell R, etal., Behav Brain Funct. 2011 Nov 25;7:48.
5. Unlearned anxiety predicts learned fear: a comparison among heterogeneous rats and the Roman rat strains. Lopez-Aumatell R, etal., Behav Brain Res. 2009 Aug 24;202(1):92-101. Epub 2009 Mar 28.
6. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Bss113 Bone structure and strength QTL 113 femur morphology trait   (VT:0000559)    
Bss114 Bone structure and strength QTL 114 femur strength trait   (VT:0010010)    
Bss115 Bone structure and strength QTL 115 femur morphology trait   (VT:0000559)    
Bss117 Bone structure and strength QTL 117 femur strength trait   (VT:0010010)    
Bss118 Bone structure and strength QTL 118 femur strength trait   (VT:0010010)    
Bss119 Bone structure and strength QTL 119 lumbar vertebra area   (VT:0010570)    
Bss120 Bone structure and strength QTL 120 femur morphology trait   (VT:0000559)    
Bss121 Bone structure and strength QTL 121 femur morphology trait   (VT:0000559)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other High and low anxious rats were tested by unconditional anxiety tests; after 3 weeks hippocampus was dissected; microarray study showed 29 down-regulated and 37 up-regulated genes between the two groups 9587424
strain_other High and low anxious rats were tested by unconditional anxiety tests; after 3 weeks amygdala was dissected; microarray study showed 6 down-regulated and 28 up-regulated genes between the two groups 9587421

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-03-14 NAft:HS  Heterogeneous stock  NJfln:HS  Heterogeneous stock  Symbol updated 68687 APPROVED
2012-03-14 NAft:HS  Heterogeneous stock  NAft:HS  Heterogeneous stock  Name updated 68913 APPROVED
2012-03-14 NAft:HS  Heterogeneous stock  NJfln:HS  Heterogeneous stock  Symbol updated 68687 APPROVED
2012-03-14 NAft:HS  Heterogeneous stock  NJfln:HS  Heterogeneous stock  Name updated 68913 APPROVED