Experimental Data Annotations Click to see Annotation Detail View
Rat Strain Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | F344.GK-(D1Mit7-D1Mgh25)/Swe | | IEA | | 7241799 | | RGD | | |
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Experimental Data Annotations Click to see Annotation Detail View
Rat Strain Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | F344.GK-(D1Mit7-D1Mgh25)/Swe | | IEA | | 7241799 | | RGD | | |
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# | Reference Title | Reference Citation |
1. | Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats. | Fakhrai-Rad H, etal., Hum Mol Genet 2000 Sep 1;9(14):2149-58. |
2. | Pathophysiological and genetic characterization of the major diabetes locus in GK rats. | Galli J, etal., Diabetes 1999 Dec;48(12):2463-70. |
3. | Separately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes. | Granhall C, etal., Diabetes. 2006 Dec;55(12):3494-500. |
4. | Phenotyping of individual pancreatic islets locates genetic defects in stimulus secretion coupling to Niddm1i within the major diabetes locus in GK rats. | Lin JM, etal., Diabetes 2001 Dec;50(12):2737-43. |
5. | RGD Strain RSO annotation pipeline | RGD Automated Pipelines |
Flank 1 / 1 (D1Mit7) |
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Flank 2 / 1 (D1Mgh25) |
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Symbol | Name | Trait |
Niddm36 | Non-insulin dependent diabetes mellitus QTL 36 |
insulin secretion trait (VT:0003564)
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Note Type | Note | Reference |
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strain_characteristics | These rats do not have any major defects in insulin secretion. | 619688 |