Strain Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Strain Registration

Strain: LEW.1AV1.DA-(D10Rat92-D10Rat135)/Ubc

Symbol: LEW.1AV1.DA-(D10Rat92-D10Rat135)/Ubc
Strain: LEW.1AV1.DA-(D10Rat92-D10Rat135)
Substrain: Ubc
RGD ID: 631595
Citation ID: RRID:RGD_631595
Ontology ID: RS:0000494
Also Known As: LEW.1AV1.DA-(D10Rat20-D10Mgh1)/Ubc; LEW.1AV1.DA-(D10Rat92-D10Rat135)/Ubc
Type: congenic
Available Source: Not Available
Origination: Biomedical Center in Uppsala, Sweden
Description: LEW.1AV1 x DA F1 was backcrossed to LEW.1AV1 for 9 generations with selection for the Oia3 locus using flanking markers, then F1N9F1 rats were used as founders for the Oia3 congenic strain.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21074,585,846 - 104,670,812RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01077,269,759 - 108,540,162RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01077,132,487 - 108,145,987RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41078,170,416 - 108,776,963RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Rats made congenic for Oia3 on chromosome 10 become susceptible to squalene-induced arthritis. Holm BC, etal., Hum Mol Genet 2001 Mar 15;10(6):565-72.
2. Identification of rat susceptibility loci for adjuvant-oil-induced arthritis. Lorentzen JC, etal., Proc Natl Acad Sci U S A 1998 May 26;95(11):6383-7
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D10Rat92)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21074,585,846 - 74,586,024 (+)MAPPER
Rnor_6.01077,269,759 - 77,269,936NCBI
Rnor_5.01077,132,487 - 77,132,664UniSTS
RGSC_v3.41078,170,545 - 78,170,722UniSTS
RGSC_v3.41078,170,416 - 78,170,722RGD
RGSC_v3.11078,184,915 - 78,185,092RGD
Celera1073,484,939 - 73,485,118UniSTS
RH 3.4 Map10681.2RGD
RH 3.4 Map10681.2UniSTS
SHRSP x BN Map1052.4899UniSTS
SHRSP x BN Map1052.4899RGD
FHH x ACI Map1060.8599RGD

Flank 2 / 1 (D10Rat135)
Rat AssemblyChrPosition (strand)Source
mRatBN7.210104,670,657 - 104,670,812 (+)MAPPER
Rnor_6.010108,540,008 - 108,540,162NCBI
Rnor_5.010108,145,833 - 108,145,987UniSTS
RGSC_v3.410108,776,808 - 108,776,963RGD
RGSC_v3.410108,776,809 - 108,776,963UniSTS
RGSC_v3.110108,791,287 - 108,791,662RGD
Celera10103,216,256 - 103,216,410UniSTS
RH 2.0 Map101397.5RGD
SHRSP x BN Map1094.1199RGD
Cytogenetic Map10q32.3UniSTS
Strain QTL Data
Symbol Name Trait
Oia3 Oil induced arthritis QTL 3 joint integrity trait   (VT:0010548)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_drgs_chems Genetically susceptible to induction of arthritis by squalene injection. 62404
strain_immunology Exhibit T lymphocyte infiltration into joints following subdermal squaline injection. 62404
strain_life_disease Displays genetic susceptibility to induction of arthritis by injection of adjuvant oil squalene. 62404