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Strain Registration

Strain: SHR.WKY-(D1Wox34-D1Rat164)/Njs

Symbol: SHR.WKY-(D1Wox34-D1Rat164)/Njs
Strain: SHR.WKY-(D1Wox34-D1Rat164)
Substrain: Njs
RGD ID: 631589
Citation ID: RRID:RGD_631589
Ontology ID: RS:0000740
Also Known As: SISA1; SHR.WKY-(D1Wox34-D1Rat164); SHR.WKY-(D1Wox34-D1Rat164)/Njs
Type: congenic
Available Source: Not Available
Origination: Dept. Cardiology, Univ of Leicester, Clinical Sciences Wing. Glenfield Hospital, Groby Rd, Leicester, UK
Description: Congenic substrain derived by backcrossing congenic strain SHR.WKY-(D1Wox19-D1Wox34) to SHR
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21164,747,424 - 166,533,203RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01175,447,029 - 177,235,302RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01182,435,050 - 184,213,712RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41168,382,195 - 170,218,440RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Genetic dissection of a blood pressure quantitative trait locus on rat chromosome 1 and gene expression analysis identifies SPON1 as a novel candidate hypertension gene. Clemitson JR, etal., Circ Res. 2007 Apr 13;100(7):992-9. Epub 2007 Mar 1.
2. Genetic dissection of region around the Sa gene on rat chromosome 1: evidence for multiple loci affecting blood pressure. Frantz S, etal., Hypertension 2001 Aug;38(2):216-21.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D1Wox34)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21164,747,424 - 164,747,558 (+)MAPPER
Rnor_6.01175,447,029 - 175,447,162NCBI
Rnor_5.01182,435,050 - 182,435,183UniSTS
RGSC_v3.41168,382,195 - 168,382,329RGD
RGSC_v3.41168,382,196 - 168,382,329UniSTS
RGSC_v3.11168,492,858 - 168,492,992RGD
Celera1162,639,018 - 162,639,151UniSTS
RH 3.4 Map11338.3UniSTS
RH 3.4 Map11338.3RGD
RH 2.0 Map1910.1RGD
Cytogenetic Map1q33UniSTS

Flank 2 / 1 (D1Rat164)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21166,532,971 - 166,533,203 (+)MAPPER
Rnor_6.01177,235,071 - 177,235,302NCBI
Rnor_5.01184,213,481 - 184,213,712UniSTS
RGSC_v3.41170,218,208 - 170,218,440RGD
RGSC_v3.41170,218,209 - 170,218,440UniSTS
RGSC_v3.11170,338,143 - 170,338,374RGD
Celera1164,408,369 - 164,408,600UniSTS
RH 3.4 Map11322.4UniSTS
RH 3.4 Map11322.4RGD
RH 2.0 Map1854.3RGD
SHRSP x BN Map183.4799RGD
FHH x ACI Map180.0199RGD
Strain QTL Data
Symbol Name Trait
Bp77 Blood pressure QTL 77 arterial blood pressure trait   (VT:2000000)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other contains at least one QTL affecting blood pressure 70855
strain_other contains the recipient strain (SHR) allele for Sah which excludes Sah as a candidate gene for this QTL affecting blood pressure 70855
strain_phys_biochem displays significantly decreased blood pressure compared to the SHR recipient strain 70855

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-27 SHR.WKY-(D1Wox34-D1Rat164)/Njs    SHR.WKY-(D1Wox34-D1Rat164)/Njs    Name updated 68913 APPROVED
2013-08-27 SHR.WKY-(D1Wox34-D1Rat164)/Njs    SHR.WKY-(D1Wox34-D1Rat164)/Njs    Name updated 68913 APPROVED