Ben Gurion University Barzilai Medical Center, Ashkelon, Israel
Bred from the original SBN colony established by Ben-Ishay at the Hebrew University Medical Center in Jerusalem. The original colony had been bred for 20+ generations but was found to be partly outbred and display phenotypic variability. To purify the colony and establish phenotypic homogeneity breeding pairs from the original colony were transferred to Ben Gurion University Barzilai Medical Center in Ashkelon, Israel in 1992 where renewed secondary breeding was performed.
Baseline systolic BP of SBH/Ygl has been measured as 127 +/-1mmHg, no sex differences between male and female rats were observed. Do not develop systolic or diastolic hypertension following 4 weeks of salt loading. DBP averaged 73 +/- 1mmHg and remained virtually unchanged after the salt loading treatment.