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Strain Registration

Strain: BN-Lx

Symbol: BN-Lx
Strain: BN-Lx
RGD ID: 61113
Citation ID: RRID:RGD_61113
Ontology ID: RS:0000114
Also Known As: BN-Lx
Type: mutant
Available Source: Not Available
Description: These were derived by introgressing mutant Lx gene of the polydactylous rat onto the BN background.
Last Known Status: Unknown

Mutant Strains
BN-Lx/Cub




Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Quantitative trait loci influencing cholesterol and phospholipid phenotypes map to chromosomes that contain genes regulating blood pressure in the spontaneously hypertensive rat. Bottger A, etal., J Clin Invest 1996 Aug 1;98(3):856-62
2. Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat. Kren V, etal., J Clin Invest 1997 Feb 15;99(4):577-81
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Scl12 Serum cholesterol level QTL 12 blood HDL cholesterol amount   (VT:0000184)    
Scl13 Serum cholesterol level QTL 13 blood HDL phospholipid amount   (VT:0010504)    
Scl23 Serum cholesterol level QTL 23 blood HDL phospholipid amount   (VT:0010504)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Mutant Lx gene is responsible for the polydactyly-luxate syndrome. The hind feet and sometimes the front feet have extra digits. 61054
strain_life_disease Mutant Lx gene is responsible for the polydactyly-luxate syndrome. The hind feet and sometimes the front feet have extra digits. 61079