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Strain Registration

Strain: SS-Sh2b3em1Mcwi-/+

Symbol: SS-Sh2b3em1Mcwi-/+
Strain: SS-Sh2b3em1-/Sh2b3em1+
Substrain: Mcwi
Full Name: SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi+
RGD ID: 5686322
Citation ID: RRID:RGD_5686322
Ontology ID: RS:0003031
Alleles: Sh2b3em1Mcwi
Also Known As: SS-Sh2b3em1Mcwi-/+; SS-Sh2b3em1Mcwi/2Mcwi; SS-Sh2b3em1Mcwi/2Mcwi; SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi+; SS-Sh2b3^[em1Mcwi-/+]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Genetic Status: Heterozygous
Last Known Status: Cryopreserved Sperm (as of 2021-11-03)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21234,750,772 - 34,750,777RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01240,262,913 - 40,262,918RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01242,132,947 - 42,136,714RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41235,954,679 - 35,958,446RGD_MAPPER_PIPELINERGSC3.4





References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Sh2b3em1Mcwi-var1 chr12 34750772 34750777 CACTTG - deletion mRatBN7.2
Sh2b3em1Mcwi-var1 chr12 40262913 40262918 CACTTG - deletion Rnor_6.0

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-26 SS-Sh2b3em1Mcwi-/+  SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi+  SS-Sh2b3em1Mcwi-/+  SS-Sh2b3em1Mcwi-/Sh2b3em1Mcwi+  Symbol and/or name change 68913 APPROVED