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Strain Registration

Strain: SS-Adra2aem1Mcwi

Symbol: SS-Adra2aem1Mcwi
Strain: SS-Adra2aem1
Substrain: Mcwi
RGD ID: 5509995
Citation ID: RRID:RGD_5509995
Ontology ID: RS:0003013
Alleles: Adra2aem1Mcwi
Also Known As: SS-Adra2aem1Mcwi; SS-Adra2a^[em1Mcwi]
Type: mutant
Available Source: Not Available
Origination: PhysGen Knockouts
Description: This strain was produced by injecting ZFNs targeting the sequence CAGGCATCCCAGGATATCctggtcACAATGGGATACCGG into SS/JrHsdMcwi rat embryos. The resulting mutation is a 47-bp frameshift deletion in exon 2.
Last Known Status: Cryopreserved Sperm (as of 2017-01-26)
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21253,061,480 - 253,064,280RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01274,766,841 - 274,766,847RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01282,178,475 - 282,181,275RGD_MAPPER_PIPELINERnor5.0






References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Adra2aem1Mcwi-var1 chr1 274766841 274766847 ATAGAGA - deletion Rnor_6.0

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-26 SS-Adra2aem1Mcwi    SS-Adra2aem1Mcwi    Symbol updated 68687 APPROVED
2014-03-26 SS-Adra2aem1Mcwi    SS-Adra2aem1Mcwi    Symbol updated 68687 APPROVED
2014-03-26 SS-Adra2aem1Mcwi    SS-Adra2aem1Mcwi    Name updated 68913 APPROVED
2014-03-26 SS-Adra2aem1Mcwi    SS-Adra2aem1Mcwi    Name updated 68913 APPROVED
2013-08-15 SS-Adra2aem1Mcwi    SS-Adra2aem1Mcwi    Name updated 68913 APPROVED
2013-08-15 SS-Adra2aem1Mcwi    SS-Adra2aem1Mcwi    Name updated 68913 APPROVED