Strain Report - Rat Genome Database

Name: SS- Prune em1Mcwi
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Strain Registration

General

Strain: SS-Prune^em1Mcwi

Symbol:

SS-Prune^em1Mcwi

Strain:

SS-Prune^em1

Substrain:

Mcwi

RGD ID:

5508364

Citation ID:

RRID:RGD_5508364

Ontology ID:

RS:0002927

Alleles:

Prune^em1Mcwi

Also Known As:

SS-Pruneem1Mcwi; SS-Prune^[em1Mcwi]

Type:

mutant

Available Source:

Not Available

Origination:

PhysGen Knockouts

Description:

This strain was produced by injecting ZFNs targeting the sequence ACCTCCGGCTTCACCATGgaggacTACTTGCAGGAC into SS/JrHsdMcwi rat embryos. The resulting mutation is a 198-bp deletion in the 5 prime URT and exon 1.

Last Known Status:

Cryopreserved Sperm (as of 2017-01-26)

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	182,858,954 - 182,859,151	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	2	196,427,714 - 196,457,105	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	2	215,924,545 - 215,954,221	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	2	190,165,356 - 190,192,807	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

References

References - curated

#	Reference Title	Reference Citation
1.	Knockout rats via embryo microinjection of zinc-finger nucleases.	Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2.	PhysGen Knockouts	PhysGen Knockout strains
3.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Allelic Variants

Name	Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Assembly
Pruneem1Mcwi-var1	chr2	182858954	182859151	CTCCAGGCTCTCCCGCCCATGGGCGAAGGGTTTGGTCCTCCAGCTCTCCCGCGTTCACCTCTGTGATCCCTCCACACCGACTGTCCGGGCTCCCCAGATCCCACACCTTCGTCCTTCCCCGACCCCACGCTGCATTCCTTTCGGTCACGGACTGAGACCCGTTACCTGCAAAGCGGCTCGACAGTCCTGCAAGTAGTC	-	deletion	mRatBN7.2

Additional Information

Nomenclature History

Date	Current Symbol	Previous Symbol	Description	Reference	Status
2014-03-26	SS-Prune^em1Mcwi	SS-Prune^em1Mcwi	Symbol updated	68687	APPROVED
2014-03-26	SS-Prune^em1Mcwi	SS-Prune^em1Mcwi	Name updated	68913	APPROVED
2014-03-26	SS-Prune^em1Mcwi	SS-Prune^em1Mcwi	Symbol updated	68687	APPROVED
2014-03-26	SS-Prune^em1Mcwi	SS-Prune^em1Mcwi	Name updated	68913	APPROVED
2013-08-14	SS-Prune^em1Mcwi	SS-Prune^em1Mcwi	Name updated	68913	APPROVED
2013-08-14	SS-Prune^em1Mcwi	SS-Prune^em1Mcwi	Name updated	68913	APPROVED
2012-01-12	SS-Prune^em1Mcwi	SS-Prune^em1Mcwi	Name updated	68913	APPROVED
2012-01-12	SS-Prune^em1Mcwi	SS-Prune^em1Mcwi	Name updated	68913	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: SS-Pruneem1Mcwi

Strain: SS-Prune^em1Mcwi