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Strain Registration

Strain: Crl:CD-Hrhr

Symbol: Crl:CD-Hrhr
Strain: CD-Hrhr
Substrain: Crl
Full Name: CD hairless rats
RGD ID: 2311078
Citation ID: RRID:RGD_2311078
Ontology ID: RS:0001826
Also Known As: Crl:CD-Hrhr; Crl:CD-Hr^[hr]
Type: outbred
Available Source: Charles River Laboratories
Origination: Charles River Laboratories
Description: This spontaneous mutation model was isolated from a Crl:CD(SD) colony in Charles River, Wilmington, MA in the late 1980s. Rederived in 1993 and subsequently transferred to Charles River, Raleigh, NC for barrier room production. The model does not exhibit the typical characteristics of hair growth and loss found in other hairless models. Specific genetic analysis to identify the mutation has not been undertaken. Histopathology has determined the model is euthymic.
Coat Color: Albino
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View
alopecia  (IAGP)


References

References - curated
# Reference Title Reference Citation
1. Strains registered by Charles River Laboratories International, Inc. Personal communication with Charles River Laboratories
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. The mouse frizzy (fr) and rat 'hairless' (frCR) mutations are natural variants of protease serine S1 family member 8 (Prss8). Spacek DV, etal., Exp Dermatol. 2010 Jun;19(6):527-32. doi: 10.1111/j.1600-0625.2009.01054.x. Epub 2010 Feb 25.

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