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Strain: BBDP/WorBrm

Symbol: BBDP/WorBrm
Strain: BBDP
Substrain: WorBrm
RGD ID: 1642018
Citation ID: RRID:RGD_1642018
Ontology ID: RS:0001182
Type: inbred
Available Source: Biomedical Research Models, Inc.
Origination: Biomedical Research Models, Inc.
Description: This strain has been maintained by brother and sister mating for 40 generations. These originated from the Worcester colony from the rats that were sent from Ottawa to Worcester in 1977. Biomedical Research Models, Inc. got these from Worcester.
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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References

References - curated
# Reference Title Reference Citation
1. Induction of type I diabetes by Kilham's rat virus in diabetes-resistant BB/Wor rats. Guberski DL, etal., Science. 1991 Nov 15;254(5034):1010-3.
2. Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat. Martin AM, etal., Diabetes 1999 Jan;48(1):50-8
3. Delayed onset and decreased incidence of diabetes in BB rats fed free radical scavengers. Murthy VK, etal., Diabetes Res Clin Pract. 1992 Oct;18(1):11-6. doi: 10.1016/0168-8227(92)90049-w.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines
5. A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes. Wallis RH, etal., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27

Region

Strain QTL Data
Symbol Name Trait
Iddm11 Insulin dependent diabetes mellitus QTL 11 blood glucose amount   (VT:0000188)    
Iddm12 Insulin dependent diabetes mellitus QTL 12 blood glucose amount   (VT:0000188)    
Iddm13 Insulin dependent diabetes mellitus QTL 13 blood glucose amount   (VT:0000188)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease The BBDP/WorBrm rat develops spontaneous and viral-induced syndromes of autoimmune diabetes mellitus. 1624306