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Strain Registration

Strain: SD-Tg(Ubc-eGFP-RNAi:Dazl)16-13Gar

Symbol: SD-Tg(Ubc-eGFP-RNAi:Dazl)16-13Gar
Strain: SD-Tg(Ubc-eGFP-RNAi:Dazl)16-13
Substrain: Gar
RGD ID: 1581617
Citation ID: RRID:RGD_1581617
Ontology ID: RS:0001404
Also Known As: Tg(Ubc-eGFP/ Dazl-shRNA)16-13Gar
Type: transgenic
Available Source: Not Available
Origination: University of Texas Southwestern Medical Center, Dallas Texas
Description: This transgenic strain was made by injecting the lentivirus vector into SD rat embryos. Founders were identified by PCR and then bred with wild-type SD rats. The vectors are derived from pLL3.7 and contains GFP and short hairpain RNA (shRNA)
Last Known Status: Unknown






References

References - curated
# Reference Title Reference Citation
1. Heritable and stable gene knockdown in rats. Dann CT, etal., Proc Natl Acad Sci U S A. 2006 Jul 14;.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other These transgenic rats were generated by RNAS interface (RNAi) technology which down-regulates Dazl gene expression by inserting a short double stranded RNA that is complimentary to the target gene. 1580353
strain_other Almost no GFP expression. 1580353
strain_phys_biochem These have minimal transgene expression; Dazl protein expression in the testes of these rats was similar to the wild-type animals. 1580353
strain_reproduction No effect on fecundity. 1580353

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-17 SD-Tg(Ubc-eGFP-RNAi:Dazl)16-13Gar    SD-Tg(Ubc-eGFP/ Dazl-shRNA)16-13Gar    Symbol updated 68687 APPROVED
2017-08-17 SD-Tg(Ubc-eGFP-RNAi:Dazl)16-13Gar    SD-Tg(Ubc-eGFP/ Dazl-shRNA)16-13Gar    Symbol updated 68687 APPROVED