Strain Report - Rat Genome Database

Name: HAS1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Strain: HAS1
Symbol:	HAS1
Strain:	HAS
Full Name:	High Alcohol Sensitive strain 1
RGD ID:	1578700
Citation ID:	RRID:RRRC_00077
Ontology ID:	RS:0001323
Also Known As:	IHAS1
Type:	inbred
Available Source:	Rat Resource and Research Center
Origination:	Rat Resource and Research Center
Description:	Selectively bred for high sensitivity for ethanol hypnosis for 24 generations then inbred
Genetic Markers:	Hooded
Last Known Status:	Cryopreserved Embryo; Cryopreserved Sperm

Experimental Data Annotations Click to see Annotation Detail View

Rat Strain

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
HAS1		IEA		7241799		RGD

Vertebrate Trait

References

References - curated

#	Reference Title	Reference Citation
1.	Selective breeding of rats differing in sensitivity to the effects of acute ethanol administration.	Draski LJ, etal., Alcohol Clin Exp Res. 1992 Feb;16(1):48-54.
2.	Developmental alterations of ethanol sensitivity in selectively bred high and low alcohol sensitive rats.	Draski LJ, etal., Pharmacol Biochem Behav. 2001 Oct-Nov;70(2-3):387-96.
3.	Data registered by the Rat Resource & Research Center	Personal Communication with Rat Resource & Research Center
4.	Quantitative trait Loci mapping for ethanol sensitivity and neurotensin receptor density in an F2 intercross derived from inbred high and low alcohol sensitivity selectively bred rat lines.	Radcliffe RA, etal., Alcohol Clin Exp Res 2004 Dec;28(12):1796-804.
5.	Confirmation of quantitative trait loci for ethanol sensitivity and neurotensin receptor density in crosses derived from the inbred high and low alcohol sensitive selectively bred rat lines.	Radcliffe RA, etal., Psychopharmacology (Berl). 2006 Oct;188(3):343-54. Epub 2006 Sep 5.
6.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines

Region

Strain QTL Data

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_other	Has alleles that contribute to high sensitivity to high dose ethanol hypnosis	1578559

External Database Links

Database	Acc Id	Source(s)
RRRC	RRRC:00077	RGD

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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