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Strain Registration

Strain: LEW/HanHfr

Symbol: LEW/HanHfr
Strain: LEW
Substrain: HanHfr
RGD ID: 1357957
Citation ID: RRID:RGD_1357957
Ontology ID: RS:0001362
Also Known As: LEW/Han@Hsd; LEW/HanHsd
Type: inbred
Available Source: ENVIGO France
Origination: ENVIGO France
Description: Inbreeding of the Lewis rat is begun by Dr. Margaret Lewis from a Wistar stock. In 1924, at F20 to Aptekmanm and Bogdon. In 1958, at F31 to Silvers, who distributed this strain. subsequently. To Central Institute for Laboratory Animal Breeding, Hannover, in 1973 at F58. In 1994, to Harlan Netherlands through acquisition of Central Institute for Laboratory Animal Breeding. Harlan became Envigo in 2015
Last Known Status: Unknown
Research Usage The LEW/HanHsd is very susceptible to the induction of EAE, while the LEW/SsNHsd is not susceptible to the induction of EAE





References

References - curated
# Reference Title Reference Citation
1. Characteristics of the aortic elastic network and related phenotypes in seven inbred rat strains. Behmoaras J, etal., Am J Physiol Heart Circ Physiol 2005 Feb;288(2):H769-77. Epub 2004 Oct 7.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_phys_biochem Have similar elastin content as WAG/RijHfr, LE/CpbHfr and WF/NHFr. 1342467

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-09-26 LEW/HanHfr    LEW/HanHfr    Name updated 68913 APPROVED