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Strain: WI-Abcb1aem2Sage

Symbol: WI-Abcb1aem2Sage
Strain: WI-Abcb1aem2Sage
RGD ID: 12907568
Citation ID: RRID:RGD_12907568
Ontology ID: RS:0004450
Alleles: Abcb1aem2Sage
Also Known As: WI-Abcb1aem2Sage; WI-Abcb1a^[em2Sage]
Type: mutant
Available Source: Not Available
Description: This model contains biallelic 19- bp deletion in exon 7 of Abcba1 gene. The homozygous knockout rats display total loss of protein via Western blot.
Genetic Status: Homozygous
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2425,413,964 - 25,413,982RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0422,396,614 - 22,396,632RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0422,276,390 - 22,448,913RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4421,709,855 - 21,796,628RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Characterization of multidrug resistance 1a/P-glycoprotein knockout rats generated by zinc finger nucleases. Chu X, etal., Mol Pharmacol. 2012 Feb;81(2):220-7. doi: 10.1124/mol.111.074179. Epub 2011 Nov 2.

Region

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Abcb1aem2Sage-var1 chr4 25413964 25413982 GAACAGGGCTGATGGCCAA - deletion mRatBN7.2
Abcb1aem2Sage-var1 chr4 22396614 22396632 GAACAGGGCTGATGGCCAA - deletion Rnor_6.0

Additional Information