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Strain Registration

Strain: SD-Prkdcem1Sage

Symbol: SD-Prkdcem1Sage
Strain: SD-Prkdcem1
Substrain: Sage
RGD ID: 12904907
Citation ID: RRID:RGD_12904907
Ontology ID: RS:0004447
Alleles: Prkdcem1Sage
Also Known As: TGRS4550 ; SD- Prkdc tm1sage; Prkdc Knockout Rat; SD-Prkdcem1Sage; SD-Prkdc^[em1Sage]
Type: mutant
Available Source: Horizon Discovery
Origination: Horizon Discovery
Description: This ZFN induced knockout rats carrying a shorter truncated gene, 872 by PCR vs 1627 in wild type, have severe combined immunodeficiency (SCID) and lack of both B and T cells
Genetic Status: Homozygous
Last Known Status: Live Animals (as of 2017-05-24)
Research Usage immunology/Inflamation and Immunodeficient
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21185,040,790 - 85,258,357RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01189,293,547 - 89,510,948RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01192,347,175 - 92,565,022RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41186,951,420 - 87,169,229RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Severe-combined immunodeficient rats can be used to generate a model of perinatal hypoxic-ischemic brain injury to facilitate studies of engrafted human neural stem cells. Beldick SR, etal., PLoS One. 2018 Nov 28;13(11):e0208105. doi: 10.1371/journal.pone.0208105. eCollection 2018.
2. Data curation from Horizon Discovery Data curation from Horizon Discovery (https://www.horizondiscovery.com/)

Region


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