Strain: SD-Abcb1aem1Sage

Symbol: SD-Abcb1aem1Sage
Strain: SD-Abcb1aem1
Substrain: Sage
Ontology ID: RS:0004432
Alleles: Abcb1aem1Sage
Also known as: TGRS3570 ; SD- Abcb1a tm1sage; Mdr1a Knockout Rat
Type: mutant
Source: Horizon Discovery
Origin: This ZFN model contains biallelic 20 bp deletion within Abcba1 gene. Animals exhibit increased oral bioavailability of P-gp-specific substrates. The homozygous knockout rats display total loss of protein via Western blot.
Genetic Status: Homozygous
Last Known Status: Live Animals (as of 2017-05-16)
Research Usage Efflux Transporter
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0422,339,829 - 22,517,642RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0422,276,390 - 22,448,913RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4421,709,855 - 21,796,628RGD_MAPPER_PIPELINERGSC3.4

Mutant Strains




Experimental Data Annotations
References - curated

Region


Additional Information

 
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Strain Nomenclature
Strain Registration

RGD Object Information
RGD ID: 12904057
Created: 2017-05-16
Species: Rattus norvegicus
Last Modified: 2017-05-16
Status: ACTIVE