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Strain Registration

Strain: SS-Trpc6em1Mcwi

Symbol: SS-Trpc6em1Mcwi
Strain: SS-Trpc6em1
Substrain: Mcwi
RGD ID: 11553912
Citation ID: RRID:RGD_11553912
Ontology ID: RS:0004225
Alleles: Trpc6em1Mcwi
Also Known As: SS-Trpc6em1Mcwi; SS-Trpc6^[em1Mcwi]
Type: mutant
Available Source: Contact MCW rat distribution at mcwcustomrats@mcw.edu
Origination: MCW Gene Editing Rat Resource Center
Description: CRISPR/Cas9 system was used to introduce a mutation in the Trpc6 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 2-bp insertion in Exon 2 of the Trpc6 gene.
Last Known Status: Cryopreserved Sperm (as of 2021-11-03)
Genotyping Protocol Download Genotyping Protocol
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.285,759,387 - 5,864,000RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.086,811,543 - 6,917,534RGD_MAPPER_PIPELINERnor6.0
Rnor_5.086,799,564 - 6,904,623RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.485,472,515 - 5,577,537RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Protective role of Trpc6 knockout in the progression of diabetic kidney disease. Spires D, etal., Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1091-F1097. doi: 10.1152/ajprenal.00155.2018. Epub 2018 Jun 20.

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